Implantable Silk Composite Microneedles for Programmable Vaccine Release Kinetics and Enhanced Immunogenicity in Transcutaneous Immunization
Microneedle vaccines mimic several aspects of cutaneous pathogen invasion by targeting antigen to skin-resident dendritic cells and triggering local inflammatory responses in the skin, which are correlated with enhanced immune responses. Here, we tested whether control over vaccine delivery kinetics...
| Main Authors: | , , , |
|---|---|
| 其他作者: | |
| 格式: | 文件 |
| 语言: | en_US |
| 出版: |
Wiley Blackwell
2015
|
| 在线阅读: | http://hdl.handle.net/1721.1/99437 |