Implantable Silk Composite Microneedles for Programmable Vaccine Release Kinetics and Enhanced Immunogenicity in Transcutaneous Immunization
Microneedle vaccines mimic several aspects of cutaneous pathogen invasion by targeting antigen to skin-resident dendritic cells and triggering local inflammatory responses in the skin, which are correlated with enhanced immune responses. Here, we tested whether control over vaccine delivery kinetics...
Main Authors: | Min, Younjin, DeMuth, Peter Charles, Irvine, Darrell J, Hammond, Paula T |
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其他作者: | Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies |
格式: | 文件 |
语言: | en_US |
出版: |
Wiley Blackwell
2015
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在线阅读: | http://hdl.handle.net/1721.1/99437 |
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