Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α

Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α

Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine that can elicit distinct cellular behaviors under different molecular contexts. Mitogen activated protein kinase (MAPK) pathways, especially the extracellular signal-regulated kinase (Erk) pathway, help to integrate influences from the...

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Bibliographic Details
Main Authors: Lau, Ken S., Gierut, Jessica, Lauffenburger, Douglas A., Haigis, Kevin M., Schrier, Sarah, Lyons, Jesse Stolberg
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2015
Online Access:http://hdl.handle.net/1721.1/99482
https://orcid.org/0000-0003-2704-0734
https://orcid.org/0000-0002-9272-4094

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