Aneuploid proliferation defects in yeast are not driven by copy number changes of a few dosage-sensitive genes
Aneuploidy—the gain or loss of one or more whole chromosome—typically has an adverse impact on organismal fitness, manifest in conditions such as Down syndrome. A central question is whether aneuploid phenotypes are the consequence of copy number changes of a few especially harmful genes that may be...
| Main Authors: | , , |
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| Format: | Article |
| Language: | en_US |
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Cold Spring Harbor Laboratory Press
2015
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| Online Access: | http://hdl.handle.net/1721.1/99646 https://orcid.org/0000-0001-9837-0314 https://orcid.org/0000-0002-6318-6119 |