Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation
Intrinsically disordered proteins/regions (IDPs/IDRs) are proteins or peptide segments that fail to form stable 3-dimensional structures in the absence of partner proteins. They are abundant in eukaryotic proteomes and are often associated with human diseases, but their biological functions have bee...
Main Authors: | Zhang, Zhengjian, Boskovic, Zarko, Hu, Wenxin, Inouye, Carla, Kim, Han-Je, Tjian, Robert, Hussain, Mahmud M., Abole, A. Katherine, Doud, Mary K., Lewis, Timothy A., Koehler, Angela Nicole, Schreiber, Stuart L. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
eLife Sciences Publications, Ltd.
2015
|
Online Access: | http://hdl.handle.net/1721.1/99670 |
Similar Items
-
TATA binding protein and associated factors in mammalian transcription : characterization of the B-TFIID activity
by: Meyers, Rachel Ellen
Published: (2006) -
Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID
by: Gupta, K, et al.
Published: (2017) -
The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo
by: Bardot, P, et al.
Published: (2017) -
Perturbed equilibria of myosin binding in airway smooth muscle and its implications in airway hyperresponsiveness and asthma
by: Inouye, David Shoichi
Published: (2005) -
Transcription Factor Inhibition: Lessons Learned and Emerging Targets
by: Chen, Andrew, et al.
Published: (2020)