The role of toll-like receptor 9 (TLR9) in autoimmunity : an examination into the relationship between gut microbiota and TLR9 in Systemic Lupus Erythematosus (SLE)
SLE is a complex autoimmune disease characterized by the production of anti-nuclear autoantibodies in a breakdown of self-tolerance. TLR9 is a receptor which recognises microorganism-associated unmethylated DNA. It is located in the endocytic pathway in B cells, dendritic cells (DCs), plasmacytoid D...
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| Format: | Thesis |
| Language: | English |
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2019
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| Online Access: | https://hdl.handle.net/10356/100426 http://hdl.handle.net/10220/48587 |