Palladacycle-catalyzed asymmetric intermolecular construction of chiral tertiary p-heterocycles by stepwise addition of H–P–H bonds to bis(enones)
A palladacycle-catalyzed diastereo- and enantioselective stepwise double hydrophosphination of bis(enones) with PhPH2 has been developed, allowing intermolecular construction of chiral tertiary bulky P-heterocycles in one pot in high yields. A catalytic cycle for the reaction is proposed as well.
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/101232 http://hdl.handle.net/10220/13697 |
| _version_ | 1826117251317628928 |
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| author | Pullarkat, Sumod A. Huang, Yinhua Teong, Siewping Chew, Renta Jonathan Li, Yongxin Leung, Pak-Hing |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Pullarkat, Sumod A. Huang, Yinhua Teong, Siewping Chew, Renta Jonathan Li, Yongxin Leung, Pak-Hing |
| author_sort | Pullarkat, Sumod A. |
| collection | NTU |
| description | A palladacycle-catalyzed diastereo- and enantioselective stepwise double hydrophosphination of bis(enones) with PhPH2 has been developed, allowing intermolecular construction of chiral tertiary bulky P-heterocycles in one pot in high yields. A catalytic cycle for the reaction is proposed as well. |
| first_indexed | 2024-10-01T04:24:33Z |
| format | Journal Article |
| id | ntu-10356/101232 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:24:33Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/1012322020-03-07T12:37:08Z Palladacycle-catalyzed asymmetric intermolecular construction of chiral tertiary p-heterocycles by stepwise addition of H–P–H bonds to bis(enones) Pullarkat, Sumod A. Huang, Yinhua Teong, Siewping Chew, Renta Jonathan Li, Yongxin Leung, Pak-Hing School of Physical and Mathematical Sciences A palladacycle-catalyzed diastereo- and enantioselective stepwise double hydrophosphination of bis(enones) with PhPH2 has been developed, allowing intermolecular construction of chiral tertiary bulky P-heterocycles in one pot in high yields. A catalytic cycle for the reaction is proposed as well. 2013-09-25T07:47:04Z 2019-12-06T20:35:26Z 2013-09-25T07:47:04Z 2019-12-06T20:35:26Z 2012 2012 Journal Article Huang, Y., Pullarkat, S. A., Teong, S., Chew, R. J., Li, Y., & Leung, P.-H. (2012). Palladacycle-Catalyzed Asymmetric Intermolecular Construction of Chiral Tertiary P-Heterocycles by Stepwise Addition of H–P–H Bonds to Bis(enones). Organometallics, 31(13), 4871–4875. https://hdl.handle.net/10356/101232 http://hdl.handle.net/10220/13697 10.1021/om300405h en Organometallics |
| spellingShingle | Pullarkat, Sumod A. Huang, Yinhua Teong, Siewping Chew, Renta Jonathan Li, Yongxin Leung, Pak-Hing Palladacycle-catalyzed asymmetric intermolecular construction of chiral tertiary p-heterocycles by stepwise addition of H–P–H bonds to bis(enones) |
| title | Palladacycle-catalyzed asymmetric intermolecular construction of chiral tertiary p-heterocycles by stepwise addition of H–P–H bonds to bis(enones) |
| title_full | Palladacycle-catalyzed asymmetric intermolecular construction of chiral tertiary p-heterocycles by stepwise addition of H–P–H bonds to bis(enones) |
| title_fullStr | Palladacycle-catalyzed asymmetric intermolecular construction of chiral tertiary p-heterocycles by stepwise addition of H–P–H bonds to bis(enones) |
| title_full_unstemmed | Palladacycle-catalyzed asymmetric intermolecular construction of chiral tertiary p-heterocycles by stepwise addition of H–P–H bonds to bis(enones) |
| title_short | Palladacycle-catalyzed asymmetric intermolecular construction of chiral tertiary p-heterocycles by stepwise addition of H–P–H bonds to bis(enones) |
| title_sort | palladacycle catalyzed asymmetric intermolecular construction of chiral tertiary p heterocycles by stepwise addition of h p h bonds to bis enones |
| url | https://hdl.handle.net/10356/101232 http://hdl.handle.net/10220/13697 |
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