Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells

Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDC) produce IFN-I in response to viruses and are routinely identified in mice by SiglecH expression. SiglecH is a sialic acid–binding Ig-like lectin that has an immunomodulatory role during viral infections. In this study, we evaluated the impact of SiglecH deficiency...

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Bibliographic Details
Main Authors: Swiecki, Melissa, Wang, Yaming, Riboldi, Elena, Kim, Alfred H. J., Dzutsev, Amiran, Gilfillan, Susan, Vermi, William, Ruedl, Christiane, Trinchieri, Giorgio, Colonna, Marco
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2014
Subjects:
DRNTU::Science::Biological sciences::Microbiology
Online Access:https://hdl.handle.net/10356/101579
http://hdl.handle.net/10220/19729

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