Optical manipulation of biological cell without measurement of cell velocity

Optical tweezer is a useful tool for non-contact micromanipulation tasks because it can manipulate biological cells precisely without causing damage to the cells. In many optical manipulation techniques, the measurement of the velocity of the cell is necessary. Since it is difficult to measure t...

Full description

Bibliographic Details
Main Authors: Cheah, Chien Chern, Li, Xiang, Yan, Xiao, Sun, Dong
Other Authors: School of Electrical and Electronic Engineering
Format: Conference Paper
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/101652
http://hdl.handle.net/10220/18882
_version_ 1826120116275773440
author Cheah, Chien Chern
Li, Xiang
Yan, Xiao
Sun, Dong
author2 School of Electrical and Electronic Engineering
author_facet School of Electrical and Electronic Engineering
Cheah, Chien Chern
Li, Xiang
Yan, Xiao
Sun, Dong
author_sort Cheah, Chien Chern
collection NTU
description Optical tweezer is a useful tool for non-contact micromanipulation tasks because it can manipulate biological cells precisely without causing damage to the cells. In many optical manipulation techniques, the measurement of the velocity of the cell is necessary. Since it is difficult to measure the velocity of the cell, the velocity information is usually obtained by differentiating the position of the cell in image space, which may result in degraded performance of the control system due to estimation error and the noises induced in differentiation. In this paper, an adaptive observer technique is proposed for optical manipulation of cell with a low Reynolds’ number, without measurement of the velocity of the cell. By using the proposed observer technique, a desired position input of the laser beam without measurement of the velocity of the cell is also developed. The stability of closed-loop system is analyzed by using Lyapunov-like method. Experimental results are presented to illustrate the performance of the proposed control method.
first_indexed 2024-10-01T05:11:16Z
format Conference Paper
id ntu-10356/101652
institution Nanyang Technological University
language English
last_indexed 2024-10-01T05:11:16Z
publishDate 2014
record_format dspace
spelling ntu-10356/1016522020-03-07T13:24:50Z Optical manipulation of biological cell without measurement of cell velocity Cheah, Chien Chern Li, Xiang Yan, Xiao Sun, Dong School of Electrical and Electronic Engineering Conference on Nanotechnology (13th : 2013 : Beijing, China) Department of Mechanical and Biomedical Engineering, City University of Hong Kong DRNTU::Engineering::Electrical and electronic engineering::Nanoelectronics Optical tweezer is a useful tool for non-contact micromanipulation tasks because it can manipulate biological cells precisely without causing damage to the cells. In many optical manipulation techniques, the measurement of the velocity of the cell is necessary. Since it is difficult to measure the velocity of the cell, the velocity information is usually obtained by differentiating the position of the cell in image space, which may result in degraded performance of the control system due to estimation error and the noises induced in differentiation. In this paper, an adaptive observer technique is proposed for optical manipulation of cell with a low Reynolds’ number, without measurement of the velocity of the cell. By using the proposed observer technique, a desired position input of the laser beam without measurement of the velocity of the cell is also developed. The stability of closed-loop system is analyzed by using Lyapunov-like method. Experimental results are presented to illustrate the performance of the proposed control method. ASTAR (Agency for Sci., Tech. and Research, S’pore) Accepted version 2014-02-28T03:45:14Z 2019-12-06T20:42:15Z 2014-02-28T03:45:14Z 2019-12-06T20:42:15Z 2013 2013 Conference Paper Cheah, C. C., Li, X., Yan, X., & Sun, D. (2013). Optical manipulation of biological cell without measurement of cell velocity. 2013 13th IEEE Conference on Nanotechnology (IEEE-NANO), 813 - 816. https://hdl.handle.net/10356/101652 http://hdl.handle.net/10220/18882 10.1109/NANO.2013.6720886 en © 2013 IEEE. This is the author created version of a work that has been peer reviewed and accepted for publication by 2013 13th IEEE Conference on Nanotechnology (IEEE-NANO), IEEE. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI:http://dx.doi.org/10.1109/NANO.2013.6720886]. 4 p. application/pdf
spellingShingle DRNTU::Engineering::Electrical and electronic engineering::Nanoelectronics
Cheah, Chien Chern
Li, Xiang
Yan, Xiao
Sun, Dong
Optical manipulation of biological cell without measurement of cell velocity
title Optical manipulation of biological cell without measurement of cell velocity
title_full Optical manipulation of biological cell without measurement of cell velocity
title_fullStr Optical manipulation of biological cell without measurement of cell velocity
title_full_unstemmed Optical manipulation of biological cell without measurement of cell velocity
title_short Optical manipulation of biological cell without measurement of cell velocity
title_sort optical manipulation of biological cell without measurement of cell velocity
topic DRNTU::Engineering::Electrical and electronic engineering::Nanoelectronics
url https://hdl.handle.net/10356/101652
http://hdl.handle.net/10220/18882
work_keys_str_mv AT cheahchienchern opticalmanipulationofbiologicalcellwithoutmeasurementofcellvelocity
AT lixiang opticalmanipulationofbiologicalcellwithoutmeasurementofcellvelocity
AT yanxiao opticalmanipulationofbiologicalcellwithoutmeasurementofcellvelocity
AT sundong opticalmanipulationofbiologicalcellwithoutmeasurementofcellvelocity