Identification of LasR ligands through a virtual screening approach

With the widespread occurrence of bacterial resistance to antibiotics, the development of new strategies beyond conventional treatments is a pursuit taken by public health institutions worldwide. LasR, a transcription factor that controls quorum sensing in Pseudomonas aeruginosa, has emerged as an a...

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Bibliographic Details
Main Authors: Skovstrup, Søren, Le Quement, Sebastian Thordal, Hansen, Thomas, Jakobsen, Tim Holm, Harmsen, Morten, Tolker-Nielsen, Tim, Nielsen, Thomas E., Givskov, Michael, Taboureau, Olivier
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/101701
http://hdl.handle.net/10220/19785