Chaperoning HMGA2 protein protects stalled replication forks in stem and cancer cells

Chaperoning HMGA2 protein protects stalled replication forks in stem and cancer cells

Maintaining genome integrity requires the accurate and complete replication of chromosomal DNA. This is of the utmost importance for embryonic stem cells (ESCs), which differentiate into cells of all lineages, including germ cells. However, endogenous and exogenous factors frequently induce stalling...

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Bibliographic Details
Main Authors: Goodman, Steven D., Tjokro, Natalia O., Yu, Haojie, Lim, Hong Hwa, Sathiyanathan, Padmapriya, Natarajan, Suchitra, Chew, Tian Wei, Klonisch, Thomas, Surana, Uttam, Dröge, Peter
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2014
Subjects:
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/102195
http://hdl.handle.net/10220/18834

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