Deformation kinetics of pH-sensitive hydrogels
Polymeric gels can undergo large deformation when subjected to external solutions of varying pH. It is imperative to understand the deformation process of pH-sensitive hydrogels for the effective application of these attractive materials in the biomedical and microfluidic fields. In the modeling of...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/102241 http://hdl.handle.net/10220/18936 |
| _version_ | 1811687906433040384 |
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| author | Toh, William Ng, Teng Yong Liu, Zishun Hu, Jianying |
| author2 | School of Mechanical and Aerospace Engineering |
| author_facet | School of Mechanical and Aerospace Engineering Toh, William Ng, Teng Yong Liu, Zishun Hu, Jianying |
| author_sort | Toh, William |
| collection | NTU |
| description | Polymeric gels can undergo large deformation when subjected to external solutions of varying pH. It is imperative to understand the deformation process of pH-sensitive hydrogels for the effective application of these attractive materials in the biomedical and microfluidic fields. In the modeling of these multi-phase materials, finite element (FE) modeling is a useful tool for the development of future applications, and it allows developers to test a wide variety of material responses in a cost-effective and efficient manner, reducing the need to conduct extensive laboratory experiments. Although a FE user-defined material model is available for the equilibrium state, the transient response of pH-sensitive gels has not been effectively modeled. Based on our recent work using the heat transfer analogy to tap into the readily available coupled temperature–displacement elements available in the commercial FE software ABAQUS for simulation of the transient swelling process of neutral hydrogels, the transient swelling process of a pH-sensitive hydrogel is studied and a FE model is further developed to simulate the transient phenomena. Some benchmark examples are investigated to demonstrate the model's capabilities in the simulation of nonlinear deformation kinetics relevant to several applications of pH-sensitive hydrogels. |
| first_indexed | 2024-10-01T05:23:45Z |
| format | Journal Article |
| id | ntu-10356/102241 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:23:45Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | ntu-10356/1022412020-03-07T13:22:14Z Deformation kinetics of pH-sensitive hydrogels Toh, William Ng, Teng Yong Liu, Zishun Hu, Jianying School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering Polymeric gels can undergo large deformation when subjected to external solutions of varying pH. It is imperative to understand the deformation process of pH-sensitive hydrogels for the effective application of these attractive materials in the biomedical and microfluidic fields. In the modeling of these multi-phase materials, finite element (FE) modeling is a useful tool for the development of future applications, and it allows developers to test a wide variety of material responses in a cost-effective and efficient manner, reducing the need to conduct extensive laboratory experiments. Although a FE user-defined material model is available for the equilibrium state, the transient response of pH-sensitive gels has not been effectively modeled. Based on our recent work using the heat transfer analogy to tap into the readily available coupled temperature–displacement elements available in the commercial FE software ABAQUS for simulation of the transient swelling process of neutral hydrogels, the transient swelling process of a pH-sensitive hydrogel is studied and a FE model is further developed to simulate the transient phenomena. Some benchmark examples are investigated to demonstrate the model's capabilities in the simulation of nonlinear deformation kinetics relevant to several applications of pH-sensitive hydrogels. 2014-03-21T06:07:52Z 2019-12-06T20:52:08Z 2014-03-21T06:07:52Z 2019-12-06T20:52:08Z 2013 2013 Journal Article Toh, W., Ng, T. Y., Liu, Z., & Hu, J. (2013). Deformation kinetics of pH-sensitive hydrogels. Polymer International, in press. 0959-8103 https://hdl.handle.net/10356/102241 http://hdl.handle.net/10220/18936 10.1002/pi.4652 en Polymer international © 2013 Society of Chemical Industry. |
| spellingShingle | DRNTU::Engineering::Mechanical engineering Toh, William Ng, Teng Yong Liu, Zishun Hu, Jianying Deformation kinetics of pH-sensitive hydrogels |
| title | Deformation kinetics of pH-sensitive hydrogels |
| title_full | Deformation kinetics of pH-sensitive hydrogels |
| title_fullStr | Deformation kinetics of pH-sensitive hydrogels |
| title_full_unstemmed | Deformation kinetics of pH-sensitive hydrogels |
| title_short | Deformation kinetics of pH-sensitive hydrogels |
| title_sort | deformation kinetics of ph sensitive hydrogels |
| topic | DRNTU::Engineering::Mechanical engineering |
| url | https://hdl.handle.net/10356/102241 http://hdl.handle.net/10220/18936 |
| work_keys_str_mv | AT tohwilliam deformationkineticsofphsensitivehydrogels AT ngtengyong deformationkineticsofphsensitivehydrogels AT liuzishun deformationkineticsofphsensitivehydrogels AT hujianying deformationkineticsofphsensitivehydrogels |