Discovery of antiviral small molecules against Hepatitis C virus

Hepatitis C virus (HCV) NS5B protein is an RNA-dependent RNA polymerase. It has a structure that resembles the right hand with a thumb, palm and finger domain. There are at least four allosteric sites in NS5B RdRp for inhibitor binding. [4th Award]

Bibliographic Details
Main Author: Li, Enlin
Other Authors: Yoon Ho Sup
Format: Student Research Poster
Language:English
Published: 2014
Online Access:https://hdl.handle.net/10356/102443
http://hdl.handle.net/10220/24257
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author Li, Enlin
author2 Yoon Ho Sup
author_facet Yoon Ho Sup
Li, Enlin
author_sort Li, Enlin
collection NTU
description Hepatitis C virus (HCV) NS5B protein is an RNA-dependent RNA polymerase. It has a structure that resembles the right hand with a thumb, palm and finger domain. There are at least four allosteric sites in NS5B RdRp for inhibitor binding. [4th Award]
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spelling ntu-10356/1024432020-09-27T20:27:53Z Discovery of antiviral small molecules against Hepatitis C virus Li, Enlin Yoon Ho Sup School of Biological Sciences Hepatitis C virus (HCV) NS5B protein is an RNA-dependent RNA polymerase. It has a structure that resembles the right hand with a thumb, palm and finger domain. There are at least four allosteric sites in NS5B RdRp for inhibitor binding. [4th Award] 2014-11-26T02:01:44Z 2019-12-06T20:55:08Z 2014-11-26T02:01:44Z 2019-12-06T20:55:08Z 2014 2014 Student Research Poster Li, E. (2014, March). Discovery of antiviral small molecules against Hepatitis C virus. Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/102443 http://hdl.handle.net/10220/24257 en © 2014 The Author(s). application/pdf
spellingShingle Li, Enlin
Discovery of antiviral small molecules against Hepatitis C virus
title Discovery of antiviral small molecules against Hepatitis C virus
title_full Discovery of antiviral small molecules against Hepatitis C virus
title_fullStr Discovery of antiviral small molecules against Hepatitis C virus
title_full_unstemmed Discovery of antiviral small molecules against Hepatitis C virus
title_short Discovery of antiviral small molecules against Hepatitis C virus
title_sort discovery of antiviral small molecules against hepatitis c virus
url https://hdl.handle.net/10356/102443
http://hdl.handle.net/10220/24257
work_keys_str_mv AT lienlin discoveryofantiviralsmallmoleculesagainsthepatitiscvirus