Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC3
Phen-DC3 is a highly promising compound that specifically targets G-quadruplexes, with potent biological effects observed in vivo. We used NMR spectroscopy to solve the structure of the complex formed between Phen-DC3 and an intramolecular G-quadruplex derived from the c-myc promoter. Structural inf...
Main Authors: | Chung, Wan Jun, Heddi, Brahim, Hamon, Florian, Teulade-Fichou, Marie-Paule, Phan, Anh Tuân |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/102946 http://hdl.handle.net/10220/19192 |
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