Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction
This study aimed at evaluating the effect of intraoperative corneal pocket irrigation in small incision lenticule extraction (SMILE) and compares it to that in femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Sixteen rabbit eyes underwent a SMILE procedure, with 8 eyes having corneal po...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2015
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| Online Access: | https://hdl.handle.net/10356/103180 http://hdl.handle.net/10220/38716 |
| _version_ | 1826124014669529088 |
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| author | Liu, Yu-Chi Jayasinghe, Lasitha Ang, Heng Pei Lwin, Nyein Chan Yam, Gary Hin Fai Mehta, Jodhbir Singh |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Liu, Yu-Chi Jayasinghe, Lasitha Ang, Heng Pei Lwin, Nyein Chan Yam, Gary Hin Fai Mehta, Jodhbir Singh |
| author_sort | Liu, Yu-Chi |
| collection | NTU |
| description | This study aimed at evaluating the effect of intraoperative corneal pocket irrigation in small incision lenticule extraction (SMILE) and compares it to that in femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Sixteen rabbit eyes underwent a SMILE procedure, with 8 eyes having corneal pocket irrigation, while the other 8 eyes were without irrigation. Another 16 eyes underwent a FS-LASIK procedure for comparison, with 8 eyes having flap irrigation, while the other 8 eyes were without irrigation. The results showed that the changes in the total corneal thickness, anterior and posterior lamellar thickness, measured by the anterior segment optical coherence tomography, were comparable between the SMILE with and without irrigation groups, suggesting that the irrigation did not lead to significant changes in the corneal thickness. However, at postoperative 8 hours, in vivo confocal microscopy showed that the interface reflectivity in the SMILE with irrigation group was significantly higher than that in other three groups. The presence of interface fluid was further confirmed by the identification of fluid pockets with undulated collagen shown on histological section in the post-SMILE with irrigation eyes. Our findings might contribute to the occurrence of post-SMILE delayed immediate visual quality recovery and further clinical study is required. |
| first_indexed | 2024-10-01T06:13:45Z |
| format | Journal Article |
| id | ntu-10356/103180 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:13:45Z |
| publishDate | 2015 |
| record_format | dspace |
| spelling | ntu-10356/1031802023-03-04T17:11:38Z Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction Liu, Yu-Chi Jayasinghe, Lasitha Ang, Heng Pei Lwin, Nyein Chan Yam, Gary Hin Fai Mehta, Jodhbir Singh School of Materials Science & Engineering School of Mechanical and Aerospace Engineering This study aimed at evaluating the effect of intraoperative corneal pocket irrigation in small incision lenticule extraction (SMILE) and compares it to that in femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Sixteen rabbit eyes underwent a SMILE procedure, with 8 eyes having corneal pocket irrigation, while the other 8 eyes were without irrigation. Another 16 eyes underwent a FS-LASIK procedure for comparison, with 8 eyes having flap irrigation, while the other 8 eyes were without irrigation. The results showed that the changes in the total corneal thickness, anterior and posterior lamellar thickness, measured by the anterior segment optical coherence tomography, were comparable between the SMILE with and without irrigation groups, suggesting that the irrigation did not lead to significant changes in the corneal thickness. However, at postoperative 8 hours, in vivo confocal microscopy showed that the interface reflectivity in the SMILE with irrigation group was significantly higher than that in other three groups. The presence of interface fluid was further confirmed by the identification of fluid pockets with undulated collagen shown on histological section in the post-SMILE with irrigation eyes. Our findings might contribute to the occurrence of post-SMILE delayed immediate visual quality recovery and further clinical study is required. Published version 2015-09-18T08:37:37Z 2019-12-06T21:06:54Z 2015-09-18T08:37:37Z 2019-12-06T21:06:54Z 2015 2015 Journal Article Liu, Y.-C., Jayasinghe, L., Ang, H. P., Lwin, N. C., Yam, G. H. F., & Mehta, J. S. (2015). Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction. BioMed Research International, 2015, 928608-. https://hdl.handle.net/10356/103180 http://hdl.handle.net/10220/38716 10.1155/2015/928608 26273659 en BioMed Research International © 2015 Yu-Chi Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. application/pdf |
| spellingShingle | Liu, Yu-Chi Jayasinghe, Lasitha Ang, Heng Pei Lwin, Nyein Chan Yam, Gary Hin Fai Mehta, Jodhbir Singh Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction |
| title | Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction |
| title_full | Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction |
| title_fullStr | Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction |
| title_full_unstemmed | Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction |
| title_short | Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction |
| title_sort | effect of intraoperative corneal stromal pocket irrigation in small incision lenticule extraction |
| url | https://hdl.handle.net/10356/103180 http://hdl.handle.net/10220/38716 |
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