Adaptation of pandemic H2N2 influenza A viruses in humans

The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains. To determine factors involved in the zoonotic origin of the 1957 pandemic, we per...

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Main Authors: Joseph, Udayan, Linster, Martin, Suzuki, Yuka, Krauss, Scott, Halpin, Rebecca A., Vijaykrishna, Dhanasekaran, Fabrizio, Thomas P., Bestebroer, Theo M., Maurer-Stroh, Sebastian, Webby, Richard J., Wentworth, David E., Fouchier, Ron A. M., Bahl, Justin, Smith, Gavin J. D.
Other Authors: Dermody, T. S.
Format: Journal Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/103217
http://hdl.handle.net/10220/25774
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author Joseph, Udayan
Linster, Martin
Suzuki, Yuka
Krauss, Scott
Halpin, Rebecca A.
Vijaykrishna, Dhanasekaran
Fabrizio, Thomas P.
Bestebroer, Theo M.
Maurer-Stroh, Sebastian
Webby, Richard J.
Wentworth, David E.
Fouchier, Ron A. M.
Bahl, Justin
Smith, Gavin J. D.
author2 Dermody, T. S.
author_facet Dermody, T. S.
Joseph, Udayan
Linster, Martin
Suzuki, Yuka
Krauss, Scott
Halpin, Rebecca A.
Vijaykrishna, Dhanasekaran
Fabrizio, Thomas P.
Bestebroer, Theo M.
Maurer-Stroh, Sebastian
Webby, Richard J.
Wentworth, David E.
Fouchier, Ron A. M.
Bahl, Justin
Smith, Gavin J. D.
author_sort Joseph, Udayan
collection NTU
description The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains. To determine factors involved in the zoonotic origin of the 1957 pandemic, we performed analyses on genetic sequences of 175 newly sequenced human and avian H2N2 virus isolates and all publicly available influenza virus genomes.
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spelling ntu-10356/1032172023-02-28T17:05:29Z Adaptation of pandemic H2N2 influenza A viruses in humans Joseph, Udayan Linster, Martin Suzuki, Yuka Krauss, Scott Halpin, Rebecca A. Vijaykrishna, Dhanasekaran Fabrizio, Thomas P. Bestebroer, Theo M. Maurer-Stroh, Sebastian Webby, Richard J. Wentworth, David E. Fouchier, Ron A. M. Bahl, Justin Smith, Gavin J. D. Dermody, T. S. School of Biological Sciences DRNTU::Science::Biological sciences::Microbiology::Virology The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains. To determine factors involved in the zoonotic origin of the 1957 pandemic, we performed analyses on genetic sequences of 175 newly sequenced human and avian H2N2 virus isolates and all publicly available influenza virus genomes. ASTAR (Agency for Sci., Tech. and Research, S’pore) Published version 2015-06-05T02:14:50Z 2019-12-06T21:07:41Z 2015-06-05T02:14:50Z 2019-12-06T21:07:41Z 2015 2015 Journal Article Joseph, U., Linster, M., Suzuki, Y., Krauss, S., Halpin, R. A., Vijaykrishna, D., et al. (2015). Adaptation of pandemic H2N2 influenza A viruses in humans. Journal of virology, 89(4), 2442-2447. https://hdl.handle.net/10356/103217 http://hdl.handle.net/10220/25774 10.1128/JVI.02590-14 25505070 en Journal of virology © 2015 American Society for Microbiology (ASM). This paper was published in Journal of Virology and is made available as an electronic reprint (preprint) with permission of American Society for Microbiology (ASM). The paper can be found at the following official DOI: [http://dx.doi.org/10.1128/JVI.02590-14]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 7 p. application/pdf
spellingShingle DRNTU::Science::Biological sciences::Microbiology::Virology
Joseph, Udayan
Linster, Martin
Suzuki, Yuka
Krauss, Scott
Halpin, Rebecca A.
Vijaykrishna, Dhanasekaran
Fabrizio, Thomas P.
Bestebroer, Theo M.
Maurer-Stroh, Sebastian
Webby, Richard J.
Wentworth, David E.
Fouchier, Ron A. M.
Bahl, Justin
Smith, Gavin J. D.
Adaptation of pandemic H2N2 influenza A viruses in humans
title Adaptation of pandemic H2N2 influenza A viruses in humans
title_full Adaptation of pandemic H2N2 influenza A viruses in humans
title_fullStr Adaptation of pandemic H2N2 influenza A viruses in humans
title_full_unstemmed Adaptation of pandemic H2N2 influenza A viruses in humans
title_short Adaptation of pandemic H2N2 influenza A viruses in humans
title_sort adaptation of pandemic h2n2 influenza a viruses in humans
topic DRNTU::Science::Biological sciences::Microbiology::Virology
url https://hdl.handle.net/10356/103217
http://hdl.handle.net/10220/25774
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