Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging
We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the r...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/103226 http://hdl.handle.net/10220/24381 |
| _version_ | 1826123976158478336 |
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| author | Kong, Kien Voon Liao, Lun-De Lam, Zhiyong Thakor, Nitish V. Leong, Weng Kee Olivo, Malini |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Kong, Kien Voon Liao, Lun-De Lam, Zhiyong Thakor, Nitish V. Leong, Weng Kee Olivo, Malini |
| author_sort | Kong, Kien Voon |
| collection | NTU |
| description | We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the rat cerebral cortex vasculature was observed using in vivo dark-field photoacoustic microscopy. |
| first_indexed | 2024-10-01T06:13:07Z |
| format | Journal Article |
| id | ntu-10356/103226 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:13:07Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | ntu-10356/1032262023-02-28T19:43:37Z Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging Kong, Kien Voon Liao, Lun-De Lam, Zhiyong Thakor, Nitish V. Leong, Weng Kee Olivo, Malini School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds We report, for the first time, the use of a water-soluble organometallic compound as a stable, reliable and high-contrast photoacoustic contrast agent. This gives a significantly higher contrast than that achievable with alternatives such as single-walled carbon nanotubes. Image enhancement of the rat cerebral cortex vasculature was observed using in vivo dark-field photoacoustic microscopy. ASTAR (Agency for Sci., Tech. and Research, S’pore) Accepted version 2014-12-09T06:02:51Z 2019-12-06T21:07:53Z 2014-12-09T06:02:51Z 2019-12-06T21:07:53Z 2014 2014 Journal Article Kong, K. V., Liao, L.-D., Lam, Z., Thakor, N. V., Leong, W. K., & Olivo, M. (2014). Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging. Chemical communications, 50(20), 2601-2603. https://hdl.handle.net/10356/103226 http://hdl.handle.net/10220/24381 10.1039/c3cc48529c en Chemical communications © 2014 Royal Society of Chemistry. This is the author created version of a work that has been peer reviewed and accepted for publication by Chemical Communications, Royal Society of Chemistry. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [Article DOI: http://dx.doi.org/10.1039/c3cc48529c]. 3 p. application/pdf |
| spellingShingle | DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds Kong, Kien Voon Liao, Lun-De Lam, Zhiyong Thakor, Nitish V. Leong, Weng Kee Olivo, Malini Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging |
| title | Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging |
| title_full | Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging |
| title_fullStr | Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging |
| title_full_unstemmed | Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging |
| title_short | Organometallic carbonyl clusters : a new class of contrast agents for photoacoustic cerebral vascular imaging |
| title_sort | organometallic carbonyl clusters a new class of contrast agents for photoacoustic cerebral vascular imaging |
| topic | DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds |
| url | https://hdl.handle.net/10356/103226 http://hdl.handle.net/10220/24381 |
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