Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery

In recent years, multifunctional nanoparticles (NPs) consisting of either metal (e.g. Au), or magnetic NP (e.g. iron oxide) with other fluorescent components such as quantum dots (QDs) or organic dyes have been emerging as versatile candidate systems for cancer diagnosis, therapy, and macromolecu...

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Main Authors: Yen, Swee Kuan, Padmanabhan, Parasuraman, Selvan, Subramanian Tamil
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/103765
http://hdl.handle.net/10220/19281
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author Yen, Swee Kuan
Padmanabhan, Parasuraman
Selvan, Subramanian Tamil
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Yen, Swee Kuan
Padmanabhan, Parasuraman
Selvan, Subramanian Tamil
author_sort Yen, Swee Kuan
collection NTU
description In recent years, multifunctional nanoparticles (NPs) consisting of either metal (e.g. Au), or magnetic NP (e.g. iron oxide) with other fluorescent components such as quantum dots (QDs) or organic dyes have been emerging as versatile candidate systems for cancer diagnosis, therapy, and macromolecule delivery such as micro ribonucleic acid (microRNA). This review intends to highlight the recent advances in the synthesis and application of multifunctional NPs (mainly iron oxide) in theranostics, an area used to combine therapeutics and diagnostics. The recent applications of NPs in miRNA delivery are also reviewed.
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spelling ntu-10356/1037652022-02-16T16:29:46Z Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery Yen, Swee Kuan Padmanabhan, Parasuraman Selvan, Subramanian Tamil Lee Kong Chian School of Medicine (LKCMedicine) DRNTU::Science::Medicine In recent years, multifunctional nanoparticles (NPs) consisting of either metal (e.g. Au), or magnetic NP (e.g. iron oxide) with other fluorescent components such as quantum dots (QDs) or organic dyes have been emerging as versatile candidate systems for cancer diagnosis, therapy, and macromolecule delivery such as micro ribonucleic acid (microRNA). This review intends to highlight the recent advances in the synthesis and application of multifunctional NPs (mainly iron oxide) in theranostics, an area used to combine therapeutics and diagnostics. The recent applications of NPs in miRNA delivery are also reviewed. ASTAR (Agency for Sci., Tech. and Research, S’pore) Published version 2014-04-30T08:06:56Z 2019-12-06T21:19:42Z 2014-04-30T08:06:56Z 2019-12-06T21:19:42Z 2013 2013 Journal Article Yen, S. K., Padmanabhan, P., & Selvan, S. T. (2013). Multifunctional Iron Oxide Nanoparticles for Diagnostics, Therapy and Macromolecule Delivery. Theranostics, 3(12), 986-1003. 1838-7640 https://hdl.handle.net/10356/103765 http://hdl.handle.net/10220/19281 10.7150/thno.4827 24396508 en Theranostics © 2013 Ivyspring International Publisher. This paper was published in Theranostics and is made available as an electronic reprint (preprint) with permission of Ivyspring International Publisher. The paper can be found at the following official DOI: [http://dx.doi.org/10.7150/thno.4827]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 18 p. application/pdf
spellingShingle DRNTU::Science::Medicine
Yen, Swee Kuan
Padmanabhan, Parasuraman
Selvan, Subramanian Tamil
Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery
title Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery
title_full Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery
title_fullStr Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery
title_full_unstemmed Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery
title_short Multifunctional iron oxide nanoparticles for diagnostics, therapy and macromolecule delivery
title_sort multifunctional iron oxide nanoparticles for diagnostics therapy and macromolecule delivery
topic DRNTU::Science::Medicine
url https://hdl.handle.net/10356/103765
http://hdl.handle.net/10220/19281
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AT selvansubramaniantamil multifunctionalironoxidenanoparticlesfordiagnosticstherapyandmacromoleculedelivery