The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet

Aims/hypothesis Physical activity improves oxidative capacity and exerts therapeutic beneficial effects, particularly in the context of metabolic diseases. The peroxisome proliferator-activated receptor (PPAR) γ coactivator-1α (PGC-1α) and the nuclear receptor PPARβ/δ have both been independently d...

Full description

Bibliographic Details
Main Authors: Pérez-Schindler, Joaquín, Svensson, Kristoffer, Vargas-Fernández, Elyzabeth, Santos, Gesa, Wahli, Walter, Handschin, Christoph
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/103785
http://hdl.handle.net/10220/24594