The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet

Aims/hypothesis Physical activity improves oxidative capacity and exerts therapeutic beneficial effects, particularly in the context of metabolic diseases. The peroxisome proliferator-activated receptor (PPAR) γ coactivator-1α (PGC-1α) and the nuclear receptor PPARβ/δ have both been independently d...

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Detalles Bibliográficos
Autores principales: Pérez-Schindler, Joaquín, Svensson, Kristoffer, Vargas-Fernández, Elyzabeth, Santos, Gesa, Wahli, Walter, Handschin, Christoph
Otros Autores: Lee Kong Chian School of Medicine (LKCMedicine)
Formato: Journal Article
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://hdl.handle.net/10356/103785
http://hdl.handle.net/10220/24594