β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis

β-functionalization of carboxylic anhydrides with β-alkyl substituents through carbene organocatalysis

The first NHC-catalyzed functionalization of carboxylic anhydrides is described. In this reaction, the β carbon behaves as a nucleophilic carbon and undergoes asymmetric reactions with electrophiles. Anhydrides with challenging β-alkyl substituents work effectively.

Bibliographic Details
Main Authors: Jin, Zhichao, Chen, Shaojin, Wang, Yuhuang, Zheng, Pengcheng, Yang, Song, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2015
Subjects:
DRNTU::Science::Chemistry::Organic chemistry::Carbanions
DRNTU::Science::Chemistry::Physical chemistry::Catalysis
Online Access:https://hdl.handle.net/10356/104027
http://hdl.handle.net/10220/24635

Internet

https://hdl.handle.net/10356/104027
http://hdl.handle.net/10220/24635

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