Incorporation of thio-pseudoisocytosine into triplex-forming peptide nucleic acids for enhanced recognition of RNA duplexes

Peptide nucleic acids (PNAs) have been developed for applications in biotechnology and therapeutics. There is great potential in the development of chemically modified PNAs or other triplex-forming ligands that selectively bind to RNA duplexes, but not single-stranded regions, at near-physiological...

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Bibliographic Details
Main Authors: Devi, Gitali, Yuan, Zhen, Lu, Yunpeng, Zhao, Yanli, Chen, Gang
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/104099
http://hdl.handle.net/10220/19542