Automated assessment of β-cell area and density per islet and patient using TMEM27 and BACE2 immunofluorescence staining in human pancreatic β-cells

In this study we aimed to establish an unbiased automatic quantification pipeline to assess islet specific features such as β-cell area and density per islet based on immunofluorescence stainings. To determine these parameters, the in vivo protein expression levels of TMEM27 and BACE2 in pancreatic...

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Bibliographic Details
Main Authors: Rechsteiner, Markus P., Floros, Xenofon, Boehm, Bernhard O., Marselli, Lorella, Marchetti, Piero, Stoffel, Markus, Moch, Holger, Spinas, Giatgen A.
Other Authors: Pietropaolo, Massimo
Format: Journal Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/105082
http://hdl.handle.net/10220/20420

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