Colorimetric detection of creatinine based on plasmonic nanoparticles via synergistic coordination chemistry

A simple and portable colorimetric assay for creatinine detection is fabricated based on the synergistic coordination of creatinine and uric acid with Hg2+ on the surface of gold nanoparticles, which exhibits good selectivity and sensitivity. Point-of-care clinical creatinine monitoring can be suppo...

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Bibliographic Details
Main Authors: Du, Jianjun, Zhu, Bowen, Leow, Wan Ru, Chen, Shi, Sum, Tze Chien, Peng, Xiaojun, Chen, Xiaodong
Other Authors: School of Materials Science & Engineering
Format: Journal Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/105207
http://hdl.handle.net/10220/25975
Description
Summary:A simple and portable colorimetric assay for creatinine detection is fabricated based on the synergistic coordination of creatinine and uric acid with Hg2+ on the surface of gold nanoparticles, which exhibits good selectivity and sensitivity. Point-of-care clinical creatinine monitoring can be supported for monitoring renal function and diagnosing corresponding renal diseases at home.