Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography
The chiral selector 6-azido-2, 3-di(p-chlorophenylcarbamoylated) cellulose was synthesized and further chemically immobilized onto 5-μm amino functionalized spherical porous silica gel. It was used as chiral stationary phase in high-performance liquid chromatography. Thirty racemates were successful...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/105703 http://hdl.handle.net/10220/17956 |
| _version_ | 1811684283509637120 |
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| author | Zhang, Zhen Bin Peng, G. M. Wu, S. Q. Fang, Z. L. Wu, S. S. Ng, S. C. Zhang, Wei-Guang Fan, Jun Zheng, Sheng-Run |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Zhang, Zhen Bin Peng, G. M. Wu, S. Q. Fang, Z. L. Wu, S. S. Ng, S. C. Zhang, Wei-Guang Fan, Jun Zheng, Sheng-Run |
| author_sort | Zhang, Zhen Bin |
| collection | NTU |
| description | The chiral selector 6-azido-2, 3-di(p-chlorophenylcarbamoylated) cellulose was synthesized and further chemically immobilized onto 5-μm amino functionalized spherical porous silica gel. It was used as chiral stationary phase in high-performance liquid chromatography. Thirty racemates were successfully separated into enantiomers in either normal phase mode or reversed-phase mode. Good reproducibility and stability of the chiral stationary phase have been demonstrated. |
| first_indexed | 2024-10-01T04:26:10Z |
| format | Journal Article |
| id | ntu-10356/105703 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T04:26:10Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/1057032023-12-29T06:47:47Z Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography Zhang, Zhen Bin Peng, G. M. Wu, S. Q. Fang, Z. L. Wu, S. S. Ng, S. C. Zhang, Wei-Guang Fan, Jun Zheng, Sheng-Run School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering The chiral selector 6-azido-2, 3-di(p-chlorophenylcarbamoylated) cellulose was synthesized and further chemically immobilized onto 5-μm amino functionalized spherical porous silica gel. It was used as chiral stationary phase in high-performance liquid chromatography. Thirty racemates were successfully separated into enantiomers in either normal phase mode or reversed-phase mode. Good reproducibility and stability of the chiral stationary phase have been demonstrated. Published Version 2013-11-29T07:31:21Z 2019-12-06T21:56:09Z 2013-11-29T07:31:21Z 2019-12-06T21:56:09Z 2012 2012 Journal Article Peng, G. M., Wu, S. Q., Fang, Z. L., Zhang, W. G., Zhang, B.Z., Fan, J., et al. (2012). Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography. Journal of chromatographic science, 50(6), 516-522. https://hdl.handle.net/10356/105703 http://hdl.handle.net/10220/17956 10.1093/chromsci/bms047 en Journal of chromatographic science © 2012 The Authors (published by Oxford University Press). This paper was published in Journal of Chromatographic Science and is made available as an electronic reprint (preprint) with permission of Oxford University Press. The paper can be found at the following official DOI: [http://dx.doi.org/10.1093/chromsci/bms047]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law application/pdf |
| spellingShingle | DRNTU::Engineering::Chemical engineering Zhang, Zhen Bin Peng, G. M. Wu, S. Q. Fang, Z. L. Wu, S. S. Ng, S. C. Zhang, Wei-Guang Fan, Jun Zheng, Sheng-Run Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography |
| title | Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography |
| title_full | Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography |
| title_fullStr | Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography |
| title_full_unstemmed | Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography |
| title_short | Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography |
| title_sort | preparation and chiral separation of a novel immobilized cellulose based chiral stationary phase in high performance liquid chromatography |
| topic | DRNTU::Engineering::Chemical engineering |
| url | https://hdl.handle.net/10356/105703 http://hdl.handle.net/10220/17956 |
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