Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing
In 3D bioprinting, printing resolution represents the deposited material in the x- and y-axes, while dimensionality defines the structural resolution of printed constructs. Dimensionality in 3D bioprinting can be defined as the resolution in the z-axis. The printing resolution, together with dimensi...
| Main Authors: | , , |
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| Format: | Journal Article |
| Language: | English |
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2019
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| Online Access: | https://hdl.handle.net/10356/105939 http://hdl.handle.net/10220/48808 |
| _version_ | 1811681004457295872 |
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| author | Lee, Jia Min Ng, Wei Long Yeong, Wai Yee |
| author2 | School of Mechanical and Aerospace Engineering |
| author_facet | School of Mechanical and Aerospace Engineering Lee, Jia Min Ng, Wei Long Yeong, Wai Yee |
| author_sort | Lee, Jia Min |
| collection | NTU |
| description | In 3D bioprinting, printing resolution represents the deposited material in the x- and y-axes, while dimensionality defines the structural resolution of printed constructs. Dimensionality in 3D bioprinting can be defined as the resolution in the z-axis. The printing resolution, together with dimensionality, contributes to the overall shape fidelity of the bioprinted constructs. The in-depth understanding of physical processes for different printing technologies is imperative in controlling the print resolution and definition. In this article, bioprinting technologies are classified according to the physical processes that deposit or form the bioprinted construct. Due to the different fabrication processes in forming fundamental printed units (voxels), the definition of printability differs for each bioprinting technique. Another aspect of resolution is the spatial positioning of cells within each fundamental building unit. The proximity of cells in the bioprinted construct affects the physiological outcomes. The second aspect of 3D bioprinting technologies is the ability to control shape fidelity. Different strategies have been used to improve the construction of a 3D engineered tissue or organ. Lastly, moving toward complex tissue printing involves adding functionalities to the bioprinted construct. Data processing, material formulations, and integration of different fabrication technologies are key areas in bioprinting that can recapture the different hierarchical aspects of native tissues. This article presents a comprehensive overview of enhancing the resolution of the bioprinting construct and identifying methods to improve functionalities of bioprinted tissues. |
| first_indexed | 2024-10-01T03:34:03Z |
| format | Journal Article |
| id | ntu-10356/105939 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:34:03Z |
| publishDate | 2019 |
| record_format | dspace |
| spelling | ntu-10356/1059392023-03-04T17:15:30Z Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing Lee, Jia Min Ng, Wei Long Yeong, Wai Yee School of Mechanical and Aerospace Engineering Singapore Centre for 3D Printing Cell Viability Rheological Properties DRNTU::Engineering::Mechanical engineering In 3D bioprinting, printing resolution represents the deposited material in the x- and y-axes, while dimensionality defines the structural resolution of printed constructs. Dimensionality in 3D bioprinting can be defined as the resolution in the z-axis. The printing resolution, together with dimensionality, contributes to the overall shape fidelity of the bioprinted constructs. The in-depth understanding of physical processes for different printing technologies is imperative in controlling the print resolution and definition. In this article, bioprinting technologies are classified according to the physical processes that deposit or form the bioprinted construct. Due to the different fabrication processes in forming fundamental printed units (voxels), the definition of printability differs for each bioprinting technique. Another aspect of resolution is the spatial positioning of cells within each fundamental building unit. The proximity of cells in the bioprinted construct affects the physiological outcomes. The second aspect of 3D bioprinting technologies is the ability to control shape fidelity. Different strategies have been used to improve the construction of a 3D engineered tissue or organ. Lastly, moving toward complex tissue printing involves adding functionalities to the bioprinted construct. Data processing, material formulations, and integration of different fabrication technologies are key areas in bioprinting that can recapture the different hierarchical aspects of native tissues. This article presents a comprehensive overview of enhancing the resolution of the bioprinting construct and identifying methods to improve functionalities of bioprinted tissues. NRF (Natl Research Foundation, S’pore) Published version 2019-06-19T01:14:50Z 2019-12-06T22:01:09Z 2019-06-19T01:14:50Z 2019-12-06T22:01:09Z 2019 Journal Article Lee, J. M., Ng, W. L., & Yeong, W. Y. (2019). Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing. Applied Physics Reviews, 6(1), 011307-. doi:10.1063/1.5053909 https://hdl.handle.net/10356/105939 http://hdl.handle.net/10220/48808 10.1063/1.5053909 en Applied Physics Reviews © 2019 The Author(s). All rights reserved. This paper was published by AIP Publishing in Applied Physics Reviews and is made available with permission of the Author(s). 16 p. application/pdf |
| spellingShingle | Cell Viability Rheological Properties DRNTU::Engineering::Mechanical engineering Lee, Jia Min Ng, Wei Long Yeong, Wai Yee Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing |
| title | Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing |
| title_full | Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing |
| title_fullStr | Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing |
| title_full_unstemmed | Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing |
| title_short | Resolution and shape in bioprinting : strategizing towards complex tissue and organ printing |
| title_sort | resolution and shape in bioprinting strategizing towards complex tissue and organ printing |
| topic | Cell Viability Rheological Properties DRNTU::Engineering::Mechanical engineering |
| url | https://hdl.handle.net/10356/105939 http://hdl.handle.net/10220/48808 |
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