Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction
The discovery of new Protein–Protein Interaction (PPI) modulators is currently limited by the difficulties associated with the design and synthesis of selective small molecule inhibitors. Peptides are a potential solution for disrupting PPIs; however, they typically suffer from poor stability in viv...
Main Authors: | Iegre, Jessica, Brear, Paul, Baker, David J., Tan, Yaw Sing, Atkinson, Eleanor L., Sore, Hannah F., O' Donovan, Daniel H., Hyvönen, Marko, Spring, David R., Verma, Chandra Shekhar |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/106361 http://hdl.handle.net/10220/49635 |
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