Identification of a new chemical class of antimalarials

Identification of a new chemical class of antimalarials

The increasing spread of drug-resistant malaria strains underscores the need for new antimalarial agents with novel modes of action (MOAs). Here, we describe a compound representative of a new class of antimalarials. This molecule, ACT-213615, potently inhibits in vitro erythrocytic growth of all te...

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Bibliographic Details
Main Authors: Bozdech, Zbynek, Brunner, Ralf, Aissaoui, Hamed, Brun, Reto, Corminboeuf, Olivier, Delahaye, Stephane, Fischli, Christoph, Boss, Christoph, Heidmann, Bibia, Kaiser, Marcel, Kamber, Jolanda, Meyer, Solange, Papastogiannidis, Petros, Siegrist, Romain, Voss, Till, Welford, Richard, Wittlin, Sergio, Binkert, Christoph
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/106461
http://hdl.handle.net/10220/12914

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