Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction
Abstract: In single input state polarization-sensitive optical coherence tomography (PS-OCT) with high resolution, the imperfections of quarter-wave plate (QWP) and the sensitivity roll-off mismatch between the two detection channels cause unpredictable polarization distortion. We present a correcti...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/106670 http://hdl.handle.net/10220/49648 http://dx.doi.org/10.1364/OE.27.006910 |
| _version_ | 1811696998021070848 |
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| author | Xiong, Qiaozhou Wang, Nanshuo Liu, Xinyu Chen, Si Liang, Haitao Chen, Shufen Liu, Linbo |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Xiong, Qiaozhou Wang, Nanshuo Liu, Xinyu Chen, Si Liang, Haitao Chen, Shufen Liu, Linbo |
| author_sort | Xiong, Qiaozhou |
| collection | NTU |
| description | Abstract: In single input state polarization-sensitive optical coherence tomography (PS-OCT) with high resolution, the imperfections of quarter-wave plate (QWP) and the sensitivity roll-off mismatch between the two detection channels cause unpredictable polarization distortion. We present a correction method based on the Jones matrix modeling of the system. In a single input PS-OCT system working at 840 nm with an axial resolution of ~2.3 μm, the method yielded better estimation of retardation and optic axis orientation with significantly reduced noise level, especially in weakly birefringent samples. Numerical simulations and quantitative imaging of a sample of known birefringence were performed to validate the performance. We further demonstrate the advantages of our approach with birefringence imaging of swine retina, rat aortic wall, and rat esophageal mucosa for potential clinical applications. |
| first_indexed | 2024-10-01T07:48:16Z |
| format | Journal Article |
| id | ntu-10356/106670 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:48:16Z |
| publishDate | 2019 |
| record_format | dspace |
| spelling | ntu-10356/1066702019-12-06T22:15:56Z Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction Xiong, Qiaozhou Wang, Nanshuo Liu, Xinyu Chen, Si Liang, Haitao Chen, Shufen Liu, Linbo School of Chemical and Biomedical Engineering School of Electrical and Electronic Engineering Optic Nerve Engineering::Electrical and electronic engineering Circular Polarization Abstract: In single input state polarization-sensitive optical coherence tomography (PS-OCT) with high resolution, the imperfections of quarter-wave plate (QWP) and the sensitivity roll-off mismatch between the two detection channels cause unpredictable polarization distortion. We present a correction method based on the Jones matrix modeling of the system. In a single input PS-OCT system working at 840 nm with an axial resolution of ~2.3 μm, the method yielded better estimation of retardation and optic axis orientation with significantly reduced noise level, especially in weakly birefringent samples. Numerical simulations and quantitative imaging of a sample of known birefringence were performed to validate the performance. We further demonstrate the advantages of our approach with birefringence imaging of swine retina, rat aortic wall, and rat esophageal mucosa for potential clinical applications. NRF (Natl Research Foundation, S’pore) ASTAR (Agency for Sci., Tech. and Research, S’pore) MOE (Min. of Education, S’pore) Published version 2019-08-15T05:05:02Z 2019-12-06T22:15:56Z 2019-08-15T05:05:02Z 2019-12-06T22:15:56Z 2019 Journal Article Xiong, Q., Wang, N., Liu, X., Chen, S., Liang, H., Chen, S., & Liu, L. (2019). Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction. Optics Express, 27(5), 6910-6924. doi:10.1364/OE.27.006910 1094-4087 https://hdl.handle.net/10356/106670 http://hdl.handle.net/10220/49648 http://dx.doi.org/10.1364/OE.27.006910 en Optics Express © 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved. 15 p. application/pdf |
| spellingShingle | Optic Nerve Engineering::Electrical and electronic engineering Circular Polarization Xiong, Qiaozhou Wang, Nanshuo Liu, Xinyu Chen, Si Liang, Haitao Chen, Shufen Liu, Linbo Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction |
| title | Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction |
| title_full | Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction |
| title_fullStr | Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction |
| title_full_unstemmed | Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction |
| title_short | Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction |
| title_sort | single input state polarization sensitive optical coherence tomography with high resolution and polarization distortion correction |
| topic | Optic Nerve Engineering::Electrical and electronic engineering Circular Polarization |
| url | https://hdl.handle.net/10356/106670 http://hdl.handle.net/10220/49648 http://dx.doi.org/10.1364/OE.27.006910 |
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