RIG-I activation by a designer short RNA ligand protects human immune cells against dengue virus infection without causing cytotoxicity
Virus-derived double-stranded RNA (dsRNA) molecules containing a triphosphate group at the 5′ end are natural ligands of retinoic acid-inducible gene I (RIG-I). The cellular pathways and proteins induced by RIG-I are an essential part of the innate immune response against viral infections. Starting...
Main Authors: | Fink, Katja, Ho, Victor, Yong, Hui Yee, Chevrier, Marion, Narang, Vipin, Lum, Josephine, Toh, Ying-Xiu, Lee, Bernett, Chen, Jinmiao, Tan, Ern Yu, Luo, Dahai |
---|---|
Other Authors: | Williams, Bryan RG. |
Format: | Journal Article |
Language: | English |
Published: |
2019
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/106854 http://hdl.handle.net/10220/49675 |
Similar Items
-
The Endogenous RIG-I Ligand Is Generated in Influenza A-Virus Infected Cells
by: Julia Steinberg, et al.
Published: (2021-08-01) -
Safety on the rig
by: University of Texas. Petroleum Extension Service
Published: (1976) -
Rig equipment/
by: 449507 Lynch, Philip F.
Published: (1981) -
The oil rig moorings handbook /
by: 337308 Vendrell, J.
Published: (1977) -
Basic rig hydraulics [slaid]
Published: (1978)