A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming

A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming

PRDM14 is an important determinant of the human embryonic stem cell (ESC) identity and works in concert with the core ESC regulators to activate pluripotency-associated genes. PRDM14 has been previously reported to exhibit repressive activity in mouse ESCs and primordial germ cells; and while PRDM14...

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Bibliographic Details
Main Authors: Su, I-hsin, Chan, Yun-Shen, Göke, Jonathan, Lu, Xinyi, Venkatesan, Nandini, Feng, Bo, Ng, Huck-Hui
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2013
Subjects:
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/106858
http://hdl.handle.net/10220/17982
http://dx.doi.org/10.1002/stem.1307

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