Correlative light and electron microscopy of telomeric repeat-binding factor 1 in mammalian cells
Telomeres are specialized nucleoprotein structures at the ends of eukaryotic chromosomes. Telomeric chromatin consists of ‘TTAGGG’ DNA repeats sequences, nucleosomes and specific telomere-binding proteins called “shelterin”. Shelterin is a six-protein complex that is essential for genome stability....
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| Format: | Thesis |
| Language: | English |
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2019
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| Online Access: | https://hdl.handle.net/10356/106933 http://hdl.handle.net/10220/50047 |