Synthesis of substituted γ- and δ-lactams through mannich-type reactions of solid-supported N -acyliminium ions
We report the results of our recent investigations into the reactivity of cyclic solid-supported N-acyliminium ions. An intermolecular Mannich-type transformation of these intermediates was used to generate libraries of substituted lactams. Masked aldehyde building blocks were readily prepared and c...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/107485 http://hdl.handle.net/10220/25576 http://dx.doi.org/10.1002/ejoc.201500054 |