Magnetic micro-devices for separation and manipulation of biological components

A scheme for magnetic based biomolecular separation, transportation and detection has been proposed, designed, fabricated and successfully demonstrated through a novel micro-fabricated magnetic system. Magnetic separation becomes a popular technique to purify or isolate cells, intracellular and biol...

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Bibliographic Details
Main Author: Qasem Ramadan
Other Authors: Chen Yu
Format: Thesis
Language:English
Published: 2008
Subjects:
Online Access:https://hdl.handle.net/10356/13318
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author Qasem Ramadan
author2 Chen Yu
author_facet Chen Yu
Qasem Ramadan
author_sort Qasem Ramadan
collection NTU
description A scheme for magnetic based biomolecular separation, transportation and detection has been proposed, designed, fabricated and successfully demonstrated through a novel micro-fabricated magnetic system. Magnetic separation becomes a popular technique to purify or isolate cells, intracellular and biological active compounds from heterogeneous mixtures. This thesis introduces and demonstrates a fully micro-magnetic system as a magnetic potential concentrator for manipulating micro/nano magnetic particles in bio- molecular separation systems. The functional components of the device are an electrically phased planar electromagnet array and magnetic pillars positioned at specific locations above the surface of the planar electromagnets. The components are located in a microfluidic chamber with a capacity of 5 l. This system presents a new tool of magnetic control for manipulating and sampling biochemical compounds.
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spelling ntu-10356/133182023-07-04T17:25:30Z Magnetic micro-devices for separation and manipulation of biological components Qasem Ramadan Chen Yu Victor Samper Poenar Daniel Puiu School of Electrical and Electronic Engineering DRNTU::Engineering::Electrical and electronic engineering::Electronic apparatus and materials DRNTU::Engineering::Electrical and electronic engineering::Molecular electronics A scheme for magnetic based biomolecular separation, transportation and detection has been proposed, designed, fabricated and successfully demonstrated through a novel micro-fabricated magnetic system. Magnetic separation becomes a popular technique to purify or isolate cells, intracellular and biological active compounds from heterogeneous mixtures. This thesis introduces and demonstrates a fully micro-magnetic system as a magnetic potential concentrator for manipulating micro/nano magnetic particles in bio- molecular separation systems. The functional components of the device are an electrically phased planar electromagnet array and magnetic pillars positioned at specific locations above the surface of the planar electromagnets. The components are located in a microfluidic chamber with a capacity of 5 l. This system presents a new tool of magnetic control for manipulating and sampling biochemical compounds. DOCTOR OF PHILOSOPHY (EEE) 2008-05-21T01:03:04Z 2008-10-20T07:24:36Z 2008-05-21T01:03:04Z 2008-10-20T07:24:36Z 2006 2006 Thesis Qasem, R. (2006). Magnetic micro-devices for separation and manipulation of biological components. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/13318 10.32657/10356/13318 en 445 p. application/pdf application/pdf
spellingShingle DRNTU::Engineering::Electrical and electronic engineering::Electronic apparatus and materials
DRNTU::Engineering::Electrical and electronic engineering::Molecular electronics
Qasem Ramadan
Magnetic micro-devices for separation and manipulation of biological components
title Magnetic micro-devices for separation and manipulation of biological components
title_full Magnetic micro-devices for separation and manipulation of biological components
title_fullStr Magnetic micro-devices for separation and manipulation of biological components
title_full_unstemmed Magnetic micro-devices for separation and manipulation of biological components
title_short Magnetic micro-devices for separation and manipulation of biological components
title_sort magnetic micro devices for separation and manipulation of biological components
topic DRNTU::Engineering::Electrical and electronic engineering::Electronic apparatus and materials
DRNTU::Engineering::Electrical and electronic engineering::Molecular electronics
url https://hdl.handle.net/10356/13318
work_keys_str_mv AT qasemramadan magneticmicrodevicesforseparationandmanipulationofbiologicalcomponents