Development of Barbier-Grignard-type alkylation reaction using unactivated alkyl halides in water.
The Barbier-Grignard-type alkylation reaction is one of the most important carbon-carbon bond formation reactions in organic synthesis. Classical methods developed for the Barbier-Grignard-type alkylation reaction are mainly limited to the use of moisture sensitive organometallic reagents such as Gr...
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| Format: | Thesis |
| Language: | English |
| Published: |
2008
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| Online Access: | http://hdl.handle.net/10356/13623 |