Incorporating modified bases and base-backbone linkers into PNAs for targeting RNA secondary structures
The structure diversity of RNA allows RNA to be involved in various biological processes. RNA secondary structures include the single-stranded (ss) loops and double-stranded (ds) stems and are involved in protein binding and gene regulation. Peptide nucleic acid (PNA) is a synthetic analog of DNA an...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/136984 |