Inhibiting S100B(ββ) for activating wild-type p53 : design of stapled peptides

S100B(ββ) is a member of the S100B protein family and is distributed in a cell-specific manner. Its levels are elevated in several cancers such as malignant melanoma and correlate directly with poor prognosis in patients. S100B(ββ) directly interacts with the tumor suppressor p53, inhibiting tetrame...

Полное описание

Библиографические подробности
Главные авторы: Kannan, Srinivasaraghavan, Aronica, Pietro G. A., Tan, Yaw Sing, Verma, Chandra Shekhar
Другие авторы: School of Biological Sciences
Формат: Journal Article
Язык:English
Опубликовано: 2020
Предметы:
Online-ссылка:https://hdl.handle.net/10356/137422