Molecular basis of amyloid-β chaperone activity of lipocalin-type prostaglandin D synthase (L-PGDS)
Misfolding and aggregation of specific proteins are involved in neurodegenerative proteinopathies like Alzheimer’s disease (AD), Parkinson’s disease (PD) and Amyotrophic lateral sclerosis (ALS), etc. AD is an irreversible, progressive neurodegenerative disease that causes memory loss and detrimental...
Main Author: | Kannaian, Bhuvaneswari |
---|---|
Other Authors: | Konstantin Pervushin |
Format: | Thesis-Doctor of Philosophy |
Language: | English |
Published: |
Nanyang Technological University
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/137482 |
Similar Items
-
Abundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-β fbrils
by: Kannaian, Bhuvaneswari, et al.
Published: (2020) -
Amyloid β chaperone — lipocalin-type prostaglandin D synthase acts as a peroxidase in the presence of heme
by: Phillips, Margaret, et al.
Published: (2022) -
Developing amyloid-β chaperone lipocalin-type prostaglandin D synthase protein as a magnetic resonance active early diagnostic tool
by: Sharma, Bhargy
Published: (2020) -
Anticholinergic drugs interact with neuroprotective chaperone L-PGDS and modulate cytotoxicity of Aβ amyloids
by: Low, Kimberly Jia Yi, et al.
Published: (2021) -
The molecular basis of pancreatic amyloid deposition in type II diabetes and the binding of congo red to amyloid
by: Ashburn, Theodore Thomas
Published: (2005)