Ytterbium-catalyzed hydroboration of aldehydes and ketones

Ytterbium-catalyzed hydroboration of aldehydes and ketones

The well-defined heavy rare-earth ytterbium iodide complex 1 (L2YbI) has been successfully employed as an efficient catalyst for the hydroboration of a wide range of aldehydes and ketones with pinacolborane (HBpin) at room temperature. The protocol requires low catalyst loadings (0.1-0.5 mol %) and...

Full description

Bibliographic Details
Main Authors: Wang, Weifan, Shen, Xingchao, Zhao, Fengyi, Jiang, Huan, Yao, Weiwei, Pullarkat, Sumod A., Xu, Li, Ma, Mengtao
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2020
Subjects:
Science::Chemistry
Ytterbium
Ketones
Online Access:https://hdl.handle.net/10356/137632
Description
Summary:The well-defined heavy rare-earth ytterbium iodide complex 1 (L2YbI) has been successfully employed as an efficient catalyst for the hydroboration of a wide range of aldehydes and ketones with pinacolborane (HBpin) at room temperature. The protocol requires low catalyst loadings (0.1-0.5 mol %) and proceeds rapidly (>99% conversion in <10 min). Additionally, catalyst 1 shows a good functional group tolerance even toward the hydroxyl and amino moieties and displays chemoselective hydroboration of aldehydes over ketones under mild conditions.

Similar Items