Supramolecular hydrogels for antimicrobial therapy
The emergence of drug-resistant microbes has become a threat to global health, and microbial infections severely limit the use of healthcare materials. To achieve efficient antimicrobial therapy, supramolecular hydrogels demonstrate unprecedented advantages in medical applications due to the tunable...
| Main Authors: | , , , , , , , , |
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| 格式: | Journal Article |
| 语言: | English |
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2020
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| 主题: | |
| 在线阅读: | https://hdl.handle.net/10356/137842 |
| _version_ | 1826122998248112128 |
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| author | Hu, Benhui Owh, Cally Chee, Pei Lin Leow, Wan Ru Liu, Xuan Wu, Yun-Long Guo, Peizhi Loh, Xian Jun Chen, Xiaodong |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Hu, Benhui Owh, Cally Chee, Pei Lin Leow, Wan Ru Liu, Xuan Wu, Yun-Long Guo, Peizhi Loh, Xian Jun Chen, Xiaodong |
| author_sort | Hu, Benhui |
| collection | NTU |
| description | The emergence of drug-resistant microbes has become a threat to global health, and microbial infections severely limit the use of healthcare materials. To achieve efficient antimicrobial therapy, supramolecular hydrogels demonstrate unprecedented advantages in medical applications due to the tunable and reversible nature of their supramolecular interactions and the capability of hydrogels to incorporate various therapeutic agents. Herein, antimicrobial hydrogels are categorized according to their inherent antimicrobial properties or based on their roles in encapsulating antimicrobial materials. Moreover, strategies to further enhance the antimicrobial efficacy of hydrogels are highlighted, such as the incorporation of antifouling agents or the enabling of response towards physiological cues. We envision that supramolecular hydrogels, in combination with modern medical technology and devices, will contribute to the development of efficient and safe systems for antimicrobial therapy. |
| first_indexed | 2024-10-01T05:57:25Z |
| format | Journal Article |
| id | ntu-10356/137842 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:57:25Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1378422023-07-14T15:56:23Z Supramolecular hydrogels for antimicrobial therapy Hu, Benhui Owh, Cally Chee, Pei Lin Leow, Wan Ru Liu, Xuan Wu, Yun-Long Guo, Peizhi Loh, Xian Jun Chen, Xiaodong School of Materials Science & Engineering Innovative Center for Flexible Devices Engineering::Materials Supramolecular Hydrogels Antimicrobial Agents The emergence of drug-resistant microbes has become a threat to global health, and microbial infections severely limit the use of healthcare materials. To achieve efficient antimicrobial therapy, supramolecular hydrogels demonstrate unprecedented advantages in medical applications due to the tunable and reversible nature of their supramolecular interactions and the capability of hydrogels to incorporate various therapeutic agents. Herein, antimicrobial hydrogels are categorized according to their inherent antimicrobial properties or based on their roles in encapsulating antimicrobial materials. Moreover, strategies to further enhance the antimicrobial efficacy of hydrogels are highlighted, such as the incorporation of antifouling agents or the enabling of response towards physiological cues. We envision that supramolecular hydrogels, in combination with modern medical technology and devices, will contribute to the development of efficient and safe systems for antimicrobial therapy. NRF (Natl Research Foundation, S’pore) Accepted version 2020-04-16T03:10:52Z 2020-04-16T03:10:52Z 2018 Journal Article Hu, B., Owh, C., Chee, P. L., Leow, W. R., Liu, X., Wu, Y.-L., . . ., Chen, X. (2018). Supramolecular hydrogels for antimicrobial therapy. Chemical Society reviews, 47(18), 6917-6929. doi:10.1039/c8cs00128f 0306-0012 https://hdl.handle.net/10356/137842 10.1039/c8cs00128f 29697128 2-s2.0-85053202748 18 47 6917 6929 en Chemical Society reviews © 2018 The Author(s) (Royal Society of Chemistry). All rights reserved. This paper was published in Chemical Society reviews and is made available with permission of The Author(s) (Royal Society of Chemistry). application/pdf |
| spellingShingle | Engineering::Materials Supramolecular Hydrogels Antimicrobial Agents Hu, Benhui Owh, Cally Chee, Pei Lin Leow, Wan Ru Liu, Xuan Wu, Yun-Long Guo, Peizhi Loh, Xian Jun Chen, Xiaodong Supramolecular hydrogels for antimicrobial therapy |
| title | Supramolecular hydrogels for antimicrobial therapy |
| title_full | Supramolecular hydrogels for antimicrobial therapy |
| title_fullStr | Supramolecular hydrogels for antimicrobial therapy |
| title_full_unstemmed | Supramolecular hydrogels for antimicrobial therapy |
| title_short | Supramolecular hydrogels for antimicrobial therapy |
| title_sort | supramolecular hydrogels for antimicrobial therapy |
| topic | Engineering::Materials Supramolecular Hydrogels Antimicrobial Agents |
| url | https://hdl.handle.net/10356/137842 |
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