Facilitating subtiligase-catalyzed peptide pigation reactions by using peptide thioester substrates
By facilitating formation of the acyl–enzyme intermediate, peptide thioesters can largely promote subtiligase-catalyzed ligation reactions over their ester counterparts. This offers a significant addition to the repertoire of enzymatic methods for protein chemical synthesis and modification.
Main Authors: | Tan, Xiaohong, Yang, Renliang, Liu, Chuan-Fa |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/138242 |
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