Facilitating subtiligase-catalyzed peptide pigation reactions by using peptide thioester substrates

Facilitating subtiligase-catalyzed peptide pigation reactions by using peptide thioester substrates

By facilitating formation of the acyl–enzyme intermediate, peptide thioesters can largely promote subtiligase-catalyzed ligation reactions over their ester counterparts. This offers a significant addition to the repertoire of enzymatic methods for protein chemical synthesis and modification.

Библиографические подробности
Главные авторы:	Tan, Xiaohong, Yang, Renliang, Liu, Chuan-Fa
Другие авторы:	School of Biological Sciences
Формат:	Journal Article
Язык:	English
Опубликовано:	2020
Предметы:	Science::Biological sciences Peptide Thioester Ligation
Online-ссылка:	https://hdl.handle.net/10356/138242

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