Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization
Through the incorporation of a silicon atom to an aryl carboxylic ester substrate, the resulting C-Si bond can be activated via the addition of a carbene catalyst on a remote site. This strategy allows for efficient functionalization of the benzylic sp3-carbons of aryl carboxylic esters.
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Online Access: | https://hdl.handle.net/10356/138275 |
| _version_ | 1811696175386984448 |
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| author | Wang, Hongling Chen, Xingkuan Li, Yongjia Wang, Jilan Wu, Shuquan Xue, Wei Yang, Song Chi, Robin Yonggui |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Wang, Hongling Chen, Xingkuan Li, Yongjia Wang, Jilan Wu, Shuquan Xue, Wei Yang, Song Chi, Robin Yonggui |
| author_sort | Wang, Hongling |
| collection | NTU |
| description | Through the incorporation of a silicon atom to an aryl carboxylic ester substrate, the resulting C-Si bond can be activated via the addition of a carbene catalyst on a remote site. This strategy allows for efficient functionalization of the benzylic sp3-carbons of aryl carboxylic esters. |
| first_indexed | 2024-10-01T07:35:11Z |
| format | Journal Article |
| id | ntu-10356/138275 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:35:11Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1382752023-02-28T19:25:55Z Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization Wang, Hongling Chen, Xingkuan Li, Yongjia Wang, Jilan Wu, Shuquan Xue, Wei Yang, Song Chi, Robin Yonggui School of Physical and Mathematical Sciences Science::Chemistry::Organic chemistry Through the incorporation of a silicon atom to an aryl carboxylic ester substrate, the resulting C-Si bond can be activated via the addition of a carbene catalyst on a remote site. This strategy allows for efficient functionalization of the benzylic sp3-carbons of aryl carboxylic esters. NRF (Natl Research Foundation, S’pore) ASTAR (Agency for Sci., Tech. and Research, S’pore) MOE (Min. of Education, S’pore) Accepted version 2020-04-30T02:41:05Z 2020-04-30T02:41:05Z 2018 Journal Article Wang, H., Chen, X., Li, Y., Wang, J., Wu, S., Xue, W., . . ., Chi, R. Y. (2017). Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization. Organic letters, 20(2), 333-336. doi:10.1021/acs.orglett.7b03544 1523-7060 https://hdl.handle.net/10356/138275 10.1021/acs.orglett.7b03544 29286252 2-s2.0-85040820257 2 20 333 336 en Organic letters © 2017 American Chemical Society. All rights reserved. This paper was published in Organic letters and is made available with permission of American Chemical Society. application/pdf |
| spellingShingle | Science::Chemistry::Organic chemistry Wang, Hongling Chen, Xingkuan Li, Yongjia Wang, Jilan Wu, Shuquan Xue, Wei Yang, Song Chi, Robin Yonggui Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization |
| title | Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization |
| title_full | Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization |
| title_fullStr | Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization |
| title_full_unstemmed | Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization |
| title_short | Addition of N-heterocyclic carbene catalyst to aryl esters induces remote C-Si bond activation and benzylic carbon functionalization |
| title_sort | addition of n heterocyclic carbene catalyst to aryl esters induces remote c si bond activation and benzylic carbon functionalization |
| topic | Science::Chemistry::Organic chemistry |
| url | https://hdl.handle.net/10356/138275 |
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