WRINKLED1 transcription factor : how much do we know about its regulatory mechanism?
Many plant species produce and build up triacylglycerol (TAG) in their seeds as a main resource to provide carbon and energy during seedling development. Plant seed oils are important not only for human diets but also as renewable feedstock of industrial uses. WRINKLED1 (WRI1), an APETALA2 (AP2) tra...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/138303 |
| _version_ | 1811696438691758080 |
|---|---|
| author | Kong, Que Ma, Wei |
| author2 | School of Biological Sciences |
| author_facet | School of Biological Sciences Kong, Que Ma, Wei |
| author_sort | Kong, Que |
| collection | NTU |
| description | Many plant species produce and build up triacylglycerol (TAG) in their seeds as a main resource to provide carbon and energy during seedling development. Plant seed oils are important not only for human diets but also as renewable feedstock of industrial uses. WRINKLED1 (WRI1), an APETALA2 (AP2) transcription factor, plays an essential role in the transcriptional regulation of TAG biosynthesis as WRI1 regulates the expression of key genes in the glycolytic and fatty acid biosynthetic pathways. Recent work has identified intrinsic structural disorder in WRI1 that may affect the stability of the protein. Furthermore, WRI1 activity is modulated by post-translational modifications and interacting partners. These progresses shed light on regulatory functions of WRI1 at the molecular levels, paving new paths to the use of WRI1 for bioengineering of TAG in plants. |
| first_indexed | 2024-10-01T07:39:22Z |
| format | Journal Article |
| id | ntu-10356/138303 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:39:22Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1383032023-02-28T16:57:08Z WRINKLED1 transcription factor : how much do we know about its regulatory mechanism? Kong, Que Ma, Wei School of Biological Sciences Science::Biological sciences Arabidopsis Transcription Factor Many plant species produce and build up triacylglycerol (TAG) in their seeds as a main resource to provide carbon and energy during seedling development. Plant seed oils are important not only for human diets but also as renewable feedstock of industrial uses. WRINKLED1 (WRI1), an APETALA2 (AP2) transcription factor, plays an essential role in the transcriptional regulation of TAG biosynthesis as WRI1 regulates the expression of key genes in the glycolytic and fatty acid biosynthetic pathways. Recent work has identified intrinsic structural disorder in WRI1 that may affect the stability of the protein. Furthermore, WRI1 activity is modulated by post-translational modifications and interacting partners. These progresses shed light on regulatory functions of WRI1 at the molecular levels, paving new paths to the use of WRI1 for bioengineering of TAG in plants. Accepted version 2020-04-30T07:36:40Z 2020-04-30T07:36:40Z 2018 Journal Article Kong, Q., & Ma, W. (2018). WRINKLED1 transcription factor : how much do we know about its regulatory mechanism? Plant Science, 272, 153-156. doi:10.1016/j.plantsci.2018.04.013 0168-9452 https://hdl.handle.net/10356/138303 10.1016/j.plantsci.2018.04.013 29807586 2-s2.0-85046083429 272 153 156 en Plant Science © 2018 Elsevier B.V. All rights reserved. This paper was published in Plant Science and is made available with permission of Elsevier B.V. application/pdf |
| spellingShingle | Science::Biological sciences Arabidopsis Transcription Factor Kong, Que Ma, Wei WRINKLED1 transcription factor : how much do we know about its regulatory mechanism? |
| title | WRINKLED1 transcription factor : how much do we know about its regulatory mechanism? |
| title_full | WRINKLED1 transcription factor : how much do we know about its regulatory mechanism? |
| title_fullStr | WRINKLED1 transcription factor : how much do we know about its regulatory mechanism? |
| title_full_unstemmed | WRINKLED1 transcription factor : how much do we know about its regulatory mechanism? |
| title_short | WRINKLED1 transcription factor : how much do we know about its regulatory mechanism? |
| title_sort | wrinkled1 transcription factor how much do we know about its regulatory mechanism |
| topic | Science::Biological sciences Arabidopsis Transcription Factor |
| url | https://hdl.handle.net/10356/138303 |
| work_keys_str_mv | AT kongque wrinkled1transcriptionfactorhowmuchdoweknowaboutitsregulatorymechanism AT mawei wrinkled1transcriptionfactorhowmuchdoweknowaboutitsregulatorymechanism |