Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples
This work reports an interferometric optical microfiber sensor functionalized with nitrogen- and sulfur-codoped carbon dots (CDs) for the detection of ferric ions (Fe3+). Compared to other CD-based ferric ion sensors, the sensing mechanism of this presented sensor is dependent on the refractive inde...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Online Access: | https://hdl.handle.net/10356/138312 |
| _version_ | 1811694248362246144 |
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| author | Yap, Stephanie Hui Kit Chan, Kok Ken Zhang, Gong Tjin, Swee Chuan Yong, Ken-Tye |
| author2 | School of Electrical and Electronic Engineering |
| author_facet | School of Electrical and Electronic Engineering Yap, Stephanie Hui Kit Chan, Kok Ken Zhang, Gong Tjin, Swee Chuan Yong, Ken-Tye |
| author_sort | Yap, Stephanie Hui Kit |
| collection | NTU |
| description | This work reports an interferometric optical microfiber sensor functionalized with nitrogen- and sulfur-codoped carbon dots (CDs) for the detection of ferric ions (Fe3+). Compared to other CD-based ferric ion sensors, the sensing mechanism of this presented sensor is dependent on the refractive index modulations due to selective Fe3+ adsorption onto the CD binding sites at the tapered region. This is the first study in which CD-based sensing was performed at the solid phase as a chelator, which does not rely on its fluorescence properties. The detection performance of the proposed sensor is not only comparable to a conventional fluorescence-based CD nanoprobe sensor but also capable of delivering quantitative analysis results and ease of translation to a sensor device for on-site detection. The presented sensor exhibits Fe3+ detection sensitivity of 0.0061 nm/(μg/L) in the linear detection range between 0 and 300 μg/L and a detection limit of 0.77 μg/L based on the Langmuir isotherm model. Finally, the potential use of the CD-functionalized optical microfiber sensor in the real environmental and biological Fe3+ monitoring applications has also been validated in this work. |
| first_indexed | 2024-10-01T07:04:33Z |
| format | Journal Article |
| id | ntu-10356/138312 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:04:33Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1383122020-05-02T06:27:04Z Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples Yap, Stephanie Hui Kit Chan, Kok Ken Zhang, Gong Tjin, Swee Chuan Yong, Ken-Tye School of Electrical and Electronic Engineering Engineering::Electrical and electronic engineering Carbon Dots Heavy Metal Ion This work reports an interferometric optical microfiber sensor functionalized with nitrogen- and sulfur-codoped carbon dots (CDs) for the detection of ferric ions (Fe3+). Compared to other CD-based ferric ion sensors, the sensing mechanism of this presented sensor is dependent on the refractive index modulations due to selective Fe3+ adsorption onto the CD binding sites at the tapered region. This is the first study in which CD-based sensing was performed at the solid phase as a chelator, which does not rely on its fluorescence properties. The detection performance of the proposed sensor is not only comparable to a conventional fluorescence-based CD nanoprobe sensor but also capable of delivering quantitative analysis results and ease of translation to a sensor device for on-site detection. The presented sensor exhibits Fe3+ detection sensitivity of 0.0061 nm/(μg/L) in the linear detection range between 0 and 300 μg/L and a detection limit of 0.77 μg/L based on the Langmuir isotherm model. Finally, the potential use of the CD-functionalized optical microfiber sensor in the real environmental and biological Fe3+ monitoring applications has also been validated in this work. NRF (Natl Research Foundation, S’pore) MOE (Min. of Education, S’pore) Accepted version 2020-05-02T06:27:04Z 2020-05-02T06:27:04Z 2019 Journal Article Yap, S. H. K., Chan, K. K., Zhang, G., Tjin, S. C., & Yong, K.-T. (2019). Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples. ACS Applied Materials & Interfaces, 11(31), 28546-28553. doi:10.1021/acsami.9b08934 1944-8252 https://hdl.handle.net/10356/138312 10.1021/acsami.9b08934 31 11 28546 28553 en ACS Applied Materials & Interfaces This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Applied Materials & Interfaces, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acsami.9b08934 application/pdf |
| spellingShingle | Engineering::Electrical and electronic engineering Carbon Dots Heavy Metal Ion Yap, Stephanie Hui Kit Chan, Kok Ken Zhang, Gong Tjin, Swee Chuan Yong, Ken-Tye Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples |
| title | Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples |
| title_full | Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples |
| title_fullStr | Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples |
| title_full_unstemmed | Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples |
| title_short | Carbon dot-functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples |
| title_sort | carbon dot functionalized interferometric optical fiber sensor for detection of ferric ions in biological samples |
| topic | Engineering::Electrical and electronic engineering Carbon Dots Heavy Metal Ion |
| url | https://hdl.handle.net/10356/138312 |
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