Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial
Keloids are a common skin disorder with significant morbidity. Itch and pain are common symptoms that affect up to 80% of patients. First-line treatment is repeated intralesional corticosteroid injections, which are painful and prone to recurrence of lesions. In a previous study, we observed that sol...
| Main Authors: | , , , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/138551 |
| _version_ | 1826115256177393664 |
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| author | Tan, Collin W X Yeo, David Chen Long Cao, Taige Tan, Wei Ding V Srivastava, Ruchir Yow, Ai Ping Tan, Wee Ping Wong, Damon Wing Kee Xu, Chenjie Tey, Hong Liang |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Tan, Collin W X Yeo, David Chen Long Cao, Taige Tan, Wei Ding V Srivastava, Ruchir Yow, Ai Ping Tan, Wee Ping Wong, Damon Wing Kee Xu, Chenjie Tey, Hong Liang |
| author_sort | Tan, Collin W X |
| collection | NTU |
| description | Keloids are a common skin disorder with significant morbidity. Itch and pain are common symptoms that affect up to 80% of patients. First-line treatment is repeated intralesional corticosteroid injections, which are painful and prone to recurrence of lesions. In a previous study, we observed that solid microneedles exhibited contact-dependent inhibition on cultured keloid and normal skin fibroblasts, in the absence of drugs. |
| first_indexed | 2024-10-01T03:52:32Z |
| format | Journal Article |
| id | ntu-10356/138551 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:52:32Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1385512020-11-01T05:15:43Z Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial Tan, Collin W X Yeo, David Chen Long Cao, Taige Tan, Wei Ding V Srivastava, Ruchir Yow, Ai Ping Tan, Wee Ping Wong, Damon Wing Kee Xu, Chenjie Tey, Hong Liang School of Chemical and Biomedical Engineering Lee Kong Chian School of Medicine (LKCMedicine) NTU-Northwestern Institute for Nanomedicine Engineering::Chemical engineering Keloid Needle Keloids are a common skin disorder with significant morbidity. Itch and pain are common symptoms that affect up to 80% of patients. First-line treatment is repeated intralesional corticosteroid injections, which are painful and prone to recurrence of lesions. In a previous study, we observed that solid microneedles exhibited contact-dependent inhibition on cultured keloid and normal skin fibroblasts, in the absence of drugs. NMRC (Natl Medical Research Council, S’pore) Accepted version 2020-05-08T03:22:40Z 2020-05-08T03:22:40Z 2018 Journal Article Tan, C. W. X., Yeo, D. C. L., Cao, T., Tan, W. D. V., Srivastava, R., Yow, A. P., . . . Tey, H. L. (2018). Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial. British Journal of Dermatology, 179(6), 1418-1419. doi:10.1111/bjd.17078 0007-0963 https://hdl.handle.net/10356/138551 10.1111/bjd.17078 30101410 2-s2.0-85054366521 6 179 1418 1419 en British Journal of Dermatology © 2018 British Association of Dermatologists. All rights reserved. This paper was published in British Journal of Dermatology and is made available with permission of British Association of Dermatologists. application/pdf |
| spellingShingle | Engineering::Chemical engineering Keloid Needle Tan, Collin W X Yeo, David Chen Long Cao, Taige Tan, Wei Ding V Srivastava, Ruchir Yow, Ai Ping Tan, Wee Ping Wong, Damon Wing Kee Xu, Chenjie Tey, Hong Liang Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial |
| title | Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial |
| title_full | Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial |
| title_fullStr | Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial |
| title_full_unstemmed | Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial |
| title_short | Drug-free microneedles in the treatment of keloids : a single-blinded intraindividual controlled clinical trial |
| title_sort | drug free microneedles in the treatment of keloids a single blinded intraindividual controlled clinical trial |
| topic | Engineering::Chemical engineering Keloid Needle |
| url | https://hdl.handle.net/10356/138551 |
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