A review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis
Infectious endophthalmitis is an important cause of vision loss worldwide. This entity most often occurs as a complication of intraocular surgery especially following cataract surgery or intravitreal injection. Endophthalmitis is regarded as a serious complication following ocular surgery and the fi...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2020
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| Online Access: | https://hdl.handle.net/10356/138807 |
| _version_ | 1811688826773438464 |
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| author | Ho, Dawn Ching Wen Agarwal, Aniruddha Lee, Cecilia S. Chhablani, Jay Gupta, Vishali Khatri, Manoj Nirmal, Jayabalan Pavesio, Carlos Agrawal, Rupesh |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Ho, Dawn Ching Wen Agarwal, Aniruddha Lee, Cecilia S. Chhablani, Jay Gupta, Vishali Khatri, Manoj Nirmal, Jayabalan Pavesio, Carlos Agrawal, Rupesh |
| author_sort | Ho, Dawn Ching Wen |
| collection | NTU |
| description | Infectious endophthalmitis is an important cause of vision loss worldwide. This entity most often occurs as a complication of intraocular surgery especially following cataract surgery or intravitreal injection. Endophthalmitis is regarded as a serious complication following ocular surgery and the final visual outcome is fundamentally contingent on timely recognition and intervention. Intravitreal and oral antibiotics in combination with pars plana vitrectomy or vitreous aspiration remain the mainstay in the management of endophthalmitis. However, significant inflammation may persist even after sterilization of the intraocular cavities with appropriate antibiotics resulting in failure of treatment. This forms the basis for the use of intravitreal corticosteroids as an adjuvant to antibiotics in the management of infectious endophthalmitis. In the index manuscript, we review the existing literature to determine the role of intravitreal corticosteroids as an adjuvant to antibiotics in treating infectious endophthalmitis, and discuss their beneficial effects and controversial concerns. |
| first_indexed | 2024-10-01T05:38:23Z |
| format | Journal Article |
| id | ntu-10356/138807 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:38:23Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1388072020-06-01T10:21:26Z A review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis Ho, Dawn Ching Wen Agarwal, Aniruddha Lee, Cecilia S. Chhablani, Jay Gupta, Vishali Khatri, Manoj Nirmal, Jayabalan Pavesio, Carlos Agrawal, Rupesh School of Materials Science & Engineering Science::Medicine Antibiotics Antifungals Infectious endophthalmitis is an important cause of vision loss worldwide. This entity most often occurs as a complication of intraocular surgery especially following cataract surgery or intravitreal injection. Endophthalmitis is regarded as a serious complication following ocular surgery and the final visual outcome is fundamentally contingent on timely recognition and intervention. Intravitreal and oral antibiotics in combination with pars plana vitrectomy or vitreous aspiration remain the mainstay in the management of endophthalmitis. However, significant inflammation may persist even after sterilization of the intraocular cavities with appropriate antibiotics resulting in failure of treatment. This forms the basis for the use of intravitreal corticosteroids as an adjuvant to antibiotics in the management of infectious endophthalmitis. In the index manuscript, we review the existing literature to determine the role of intravitreal corticosteroids as an adjuvant to antibiotics in treating infectious endophthalmitis, and discuss their beneficial effects and controversial concerns. 2020-05-13T01:57:15Z 2020-05-13T01:57:15Z 2016 Journal Article Ho, D. C. W., Agarwal, A., Lee, C. S., Chhablani, J., Gupta, V., Khatri, M., . . . Agrawal, R. (2018). A review of the role of Intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis. Ocular Immunology and Inflammation, 26(3), 461-468. doi:10.1080/09273948.2016.1245758 0927-3948 https://hdl.handle.net/10356/138807 10.1080/09273948.2016.1245758 27849402 2-s2.0-84995451141 3 26 461 468 en Ocular Immunology and Inflammation © 2018 Taylor & Francis Group, LLC. All rights reserved. |
| spellingShingle | Science::Medicine Antibiotics Antifungals Ho, Dawn Ching Wen Agarwal, Aniruddha Lee, Cecilia S. Chhablani, Jay Gupta, Vishali Khatri, Manoj Nirmal, Jayabalan Pavesio, Carlos Agrawal, Rupesh A review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis |
| title | A review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis |
| title_full | A review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis |
| title_fullStr | A review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis |
| title_full_unstemmed | A review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis |
| title_short | A review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis |
| title_sort | review of the role of intravitreal corticosteroids as an adjuvant to antibiotics in infectious endophthalmitis |
| topic | Science::Medicine Antibiotics Antifungals |
| url | https://hdl.handle.net/10356/138807 |
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