Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement
Particle patterning and hopping has attracted much attention owing to their extensive involvement in many physical and biological studies. Here, by configuring an intriguing Optofluidic, we are able to pattern 500 nm particles into a 2D array in the flow stream. We also achieve a 2D patterning of cr...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Conference Paper |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/138920 |
| _version_ | 1826121699665379328 |
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| author | Shi, Yuzhi Xiong, Sha Zhang, Yantong Chin, Lip Ket Wu, J. H. Chen, T. N. Liu, Ai Qun |
| author2 | School of Electrical and Electronic Engineering |
| author_facet | School of Electrical and Electronic Engineering Shi, Yuzhi Xiong, Sha Zhang, Yantong Chin, Lip Ket Wu, J. H. Chen, T. N. Liu, Ai Qun |
| author_sort | Shi, Yuzhi |
| collection | NTU |
| description | Particle patterning and hopping has attracted much attention owing to their extensive involvement in many physical and biological studies. Here, by configuring an intriguing Optofluidic, we are able to pattern 500 nm particles into a 2D array in the flow stream. We also achieve a 2D patterning of cryptosporidium in the microchannel. By investing particle-particle interactions, we studies the long ignored new particle hopping mechanisms, and used them to screen antibodies. Our observed particle hopping in the flow stream completes the family of particle kinetics in optofluidic potential wells and inspires new minds in the develop new light fields in the microchannel. The 2D patterning of particles facilites the parallel culture and study of multiple biological samples in the flow stream. |
| first_indexed | 2024-10-01T05:36:28Z |
| format | Conference Paper |
| id | ntu-10356/138920 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:36:28Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1389202020-05-14T02:50:13Z Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement Shi, Yuzhi Xiong, Sha Zhang, Yantong Chin, Lip Ket Wu, J. H. Chen, T. N. Liu, Ai Qun School of Electrical and Electronic Engineering School of Mechanical and Aerospace Engineering Proceedings of SPIE - Optical Trapping and Optical Micromanipulation XV 2018 Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics Particle Hopping Optical Manipulation Particle patterning and hopping has attracted much attention owing to their extensive involvement in many physical and biological studies. Here, by configuring an intriguing Optofluidic, we are able to pattern 500 nm particles into a 2D array in the flow stream. We also achieve a 2D patterning of cryptosporidium in the microchannel. By investing particle-particle interactions, we studies the long ignored new particle hopping mechanisms, and used them to screen antibodies. Our observed particle hopping in the flow stream completes the family of particle kinetics in optofluidic potential wells and inspires new minds in the develop new light fields in the microchannel. The 2D patterning of particles facilites the parallel culture and study of multiple biological samples in the flow stream. NRF (Natl Research Foundation, S’pore) Published version 2020-05-14T02:50:13Z 2020-05-14T02:50:13Z 2018 Conference Paper Shi, Y. Z., Xiong, S., Zhang, Y., Chin, L. K., Wu, J. H., Chen, T. N., & Liu, A. Q. (2018). Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement. Proceedings of SPIE - Optical Trapping and Optical Micromanipulation XV 2018, 10723, 107231Y-. doi:10.1117/12.2319693 9781510620179 https://hdl.handle.net/10356/138920 10.1117/12.2319693 2-s2.0-85055531669 10723 en Copyright 2018 Society of Photo-Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. application/pdf |
| spellingShingle | Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics Particle Hopping Optical Manipulation Shi, Yuzhi Xiong, Sha Zhang, Yantong Chin, Lip Ket Wu, J. H. Chen, T. N. Liu, Ai Qun Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement |
| title | Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement |
| title_full | Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement |
| title_fullStr | Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement |
| title_full_unstemmed | Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement |
| title_short | Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement |
| title_sort | controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement |
| topic | Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics Particle Hopping Optical Manipulation |
| url | https://hdl.handle.net/10356/138920 |
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