Targeted therapy for the post-operative conjunctiva : SPARC silencing reduces collagen deposition

Targeted therapy for the post-operative conjunctiva : SPARC silencing reduces collagen deposition

Background: To develop targeted antifibrotic therapy for glaucoma filtration surgery; this study determines the effectiveness of small interfering RNA (siRNA) to reduce in vivo secreted protein acidic and rich in cysteine (SPARC) expression using the mouse model of conjunctival scarring. Methods: Ex...

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Bibliographic Details
Main Authors: Seet, Li Fong, Tan, Yang Fei, Toh, Li Zhen, Chu, Stephanie Wai Ling, Lee, Ying Shi, Venkatraman, Subbu Subramanian, Wong, Tina Tzee Ling
Other Authors: School of Materials Science & Engineering
Format: Journal Article
Language:English
Published: 2020
Subjects:
Engineering::Materials
Science::Medicine
Conjunctiva
Experimental-animal Models
Online Access:https://hdl.handle.net/10356/138940

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