Simplifying skin disease diagnosis with topical nanotechnology
A new study published in the journal Nature Biomedical Engineering1 documents a novel diagnostic technology that exploits topically applied nanotechnology to detect skin tissue biomarkers for diagnosis. This concept is demonstrated by noninvasively imaging connective tissue growth factor (CTGF) mRNA...
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| Format: | Journal Article |
| Language: | English |
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2020
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| Online Access: | https://hdl.handle.net/10356/139082 |
| _version_ | 1811693043156254720 |
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| author | Yeo, David Chenloong Xu, Chenjie |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Yeo, David Chenloong Xu, Chenjie |
| author_sort | Yeo, David Chenloong |
| collection | NTU |
| description | A new study published in the journal Nature Biomedical Engineering1 documents a novel diagnostic technology that exploits topically applied nanotechnology to detect skin tissue biomarkers for diagnosis. This concept is demonstrated by noninvasively imaging connective tissue growth factor (CTGF) mRNA in abnormal scar cells, whole tissue, and animal models. In this commentary, we highlight the main findings and discuss their implications. Successful implementation in the clinic could give rise to self-applied, biopsy-free diagnostic technology and significantly reduce healthcare burden. Crucially, noninvasive visualization of disease biomarkers, mobile device signal acquisition, and Internet-enabled transmission could significantly transform the diagnosis of skin disease and other superficial tissues. |
| first_indexed | 2024-10-01T06:45:24Z |
| format | Journal Article |
| id | ntu-10356/139082 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T06:45:24Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1390822020-05-15T05:44:58Z Simplifying skin disease diagnosis with topical nanotechnology Yeo, David Chenloong Xu, Chenjie School of Chemical and Biomedical Engineering NTU-Northwestern Institute for Nanomedicine Engineering::Chemical engineering Transdermal Nanotechnology Abnormal Scars A new study published in the journal Nature Biomedical Engineering1 documents a novel diagnostic technology that exploits topically applied nanotechnology to detect skin tissue biomarkers for diagnosis. This concept is demonstrated by noninvasively imaging connective tissue growth factor (CTGF) mRNA in abnormal scar cells, whole tissue, and animal models. In this commentary, we highlight the main findings and discuss their implications. Successful implementation in the clinic could give rise to self-applied, biopsy-free diagnostic technology and significantly reduce healthcare burden. Crucially, noninvasive visualization of disease biomarkers, mobile device signal acquisition, and Internet-enabled transmission could significantly transform the diagnosis of skin disease and other superficial tissues. 2020-05-15T05:44:58Z 2020-05-15T05:44:58Z 2018 Journal Article Yeo, D. C., & Xu, C. (2018). Simplifying skin disease diagnosis with topical nanotechnology. SLAS Technology, 23(4), 401-403. doi:10.1177/2472630318775314 2472-6303 https://hdl.handle.net/10356/139082 10.1177/2472630318775314 29772963 2-s2.0-85047387635 4 23 401 403 en SLAS Technology © 2018 Society for Laboratory Automation and Screening (published by SAGE). All rights reserved. |
| spellingShingle | Engineering::Chemical engineering Transdermal Nanotechnology Abnormal Scars Yeo, David Chenloong Xu, Chenjie Simplifying skin disease diagnosis with topical nanotechnology |
| title | Simplifying skin disease diagnosis with topical nanotechnology |
| title_full | Simplifying skin disease diagnosis with topical nanotechnology |
| title_fullStr | Simplifying skin disease diagnosis with topical nanotechnology |
| title_full_unstemmed | Simplifying skin disease diagnosis with topical nanotechnology |
| title_short | Simplifying skin disease diagnosis with topical nanotechnology |
| title_sort | simplifying skin disease diagnosis with topical nanotechnology |
| topic | Engineering::Chemical engineering Transdermal Nanotechnology Abnormal Scars |
| url | https://hdl.handle.net/10356/139082 |
| work_keys_str_mv | AT yeodavidchenloong simplifyingskindiseasediagnosiswithtopicalnanotechnology AT xuchenjie simplifyingskindiseasediagnosiswithtopicalnanotechnology |