Metabolomics reveals that dietary xenoestrogens alter cellular metabolism induced by palbociclib/letrozole combination cancer therapy
Recently, the palbociclib/letrozole combination therapy was granted accelerated US FDA approval for the treatment of estrogen receptor (ER)-positive breast cancer. Since the underlying metabolic effects of these drugs are yet unknown, we investigated their synergism at the metabolome level in MCF-7...
Main Authors: | Warth, Benedikt, Raffeiner, Philipp, Granados, Ana, Huan, Tao, Fang, Mingliang, Forsberg, Erica M., Benton, H. Paul, Goetz, Laura, Johnson, Caroline H., Siuzdak, Gary |
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Other Authors: | School of Civil and Environmental Engineering |
Format: | Journal Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/139116 |
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