Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins
A practical palladium-catalyzed ortho-olefination of O-acetyl cyanohydrins assisted by synergetic directing groups has been developed. Thus, a range of olefinated O-acetyl cyanohydrins were synthesized in moderate to good yields. The reaction occurs efficiently with high regioselectivity and with a...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
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2020
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| Online Access: | https://hdl.handle.net/10356/139183 |
| _version_ | 1824455816441233408 |
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| author | Liang, Qiu-Ju Jiang, Bing Xu, Yun-He Loh, Teck-Peng |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Liang, Qiu-Ju Jiang, Bing Xu, Yun-He Loh, Teck-Peng |
| author_sort | Liang, Qiu-Ju |
| collection | NTU |
| description | A practical palladium-catalyzed ortho-olefination of O-acetyl cyanohydrins assisted by synergetic directing groups has been developed. Thus, a range of olefinated O-acetyl cyanohydrins were synthesized in moderate to good yields. The reaction occurs efficiently with high regioselectivity and with a satisfactory tolerance of functional groups. |
| first_indexed | 2025-02-19T03:44:13Z |
| format | Journal Article |
| id | ntu-10356/139183 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-02-19T03:44:13Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ntu-10356/1391832020-05-18T02:27:54Z Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins Liang, Qiu-Ju Jiang, Bing Xu, Yun-He Loh, Teck-Peng School of Physical and Mathematical Sciences Science::Chemistry Chemical Reactions Organic Compounds A practical palladium-catalyzed ortho-olefination of O-acetyl cyanohydrins assisted by synergetic directing groups has been developed. Thus, a range of olefinated O-acetyl cyanohydrins were synthesized in moderate to good yields. The reaction occurs efficiently with high regioselectivity and with a satisfactory tolerance of functional groups. 2020-05-18T02:27:39Z 2020-05-18T02:27:39Z 2018 Journal Article Liang, Q.-J., Jiang, B., Xu, Y.-H., & Loh, T.-P. (2018). Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins. The Journal of Organic Chemistry, 83(15), 8265-8271. doi:10.1021/acs.joc.8b00991 0022-3263 https://hdl.handle.net/10356/139183 10.1021/acs.joc.8b00991 29902382 2-s2.0-85048668406 15 83 8265 8271 en The Journal of Organic Chemistry © 2018 American Chemical Society. All rights reserved. |
| spellingShingle | Science::Chemistry Chemical Reactions Organic Compounds Liang, Qiu-Ju Jiang, Bing Xu, Yun-He Loh, Teck-Peng Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins |
| title | Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins |
| title_full | Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins |
| title_fullStr | Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins |
| title_full_unstemmed | Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins |
| title_short | Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins |
| title_sort | palladium catalyzed regioselective olefination of o acetyl cyanohydrins |
| topic | Science::Chemistry Chemical Reactions Organic Compounds |
| url | https://hdl.handle.net/10356/139183 |
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